Spence R A, MacKenzie G, Anderson J R, Lyons A R, Bell M
Cancer. 1985 Feb 1;55(3):648-52. doi: 10.1002/1097-0142(19850201)55:3<648::aid-cncr2820550329>3.0.co;2-3.
Eighty-one patients with cancer of the male breast were studied. The majority (79) presented with a mass in the breast and in 8 patients the tumor was found by chance. Two patients presented with serosanguinous discharge. Average duration of symptoms was 11.9 months. Thirty patients had Stage I, 25 had Stage II, 16 had Stage III, and 8 had Stage IV disease. Fifty-three patients had simple mastectomy, nine had lumpectomy, six had radical mastectomy, and five had biopsy only. Eight had no local surgery. Overall 5- and 10-year survival allowing for all causes of death was 38% and 17%, respectively. Cox's (1972) proportional hazard regression model was used to assess the contribution of various factors to survival. Age at presentation, postoperative hormone therapy, postoperative radiotherapy, site of the primary tumor within the breast, and type of local surgery did not contribute to survival. Only the stage of disease contributed to survival and did so in the expected direction.
对81例男性乳腺癌患者进行了研究。大多数患者（79例）表现为乳房肿块，8例患者的肿瘤是偶然发现的。2例患者出现浆液性血性溢液。症状的平均持续时间为11.9个月。30例患者为Ⅰ期，25例为Ⅱ期，16例为Ⅲ期，8例为Ⅳ期疾病。53例患者接受了单纯乳房切除术，9例接受了肿块切除术，6例接受了根治性乳房切除术，5例仅接受了活检。8例未进行局部手术。考虑到所有死亡原因，总体5年和10年生存率分别为38%和17%。使用Cox（1972年）比例风险回归模型评估各种因素对生存的影响。就诊时的年龄、术后激素治疗、术后放疗、乳房内原发肿瘤的部位以及局部手术的类型对生存没有影响。只有疾病分期对生存有影响，且影响方向符合预期。
