与鼻窦内翻性乳头状瘤复发相关的上皮-间质转化标志物表达增加。

Increased expression of epithelial-mesenchymal transition markers associated with recurrence of sinonasal inverted papilloma.

作者信息

Tu Junhao, Jiang Fan, Liu Jing, Ong Hsiao Hui, Huang Zhiqun, Wang Keshuang, Luo Qing, Shi Li, Ye Jing, Wang Deyun

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, The First Affiliated Hospital, Jiangxi Medical College, Nanchang University, Nanchang, China.

Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, National University Health System, Singapore, Singapore.

出版信息

Int Forum Allergy Rhinol. 2025 Mar;15(3):354-358. doi: 10.1002/alr.23501. Epub 2024 Dec 9.

DOI:10.1002/alr.23501

PMID:39652071

Abstract

Sinonasal inverted papilloma (SNIP) is a benign epithelial proliferative disease with a high recurrence rate. The role of epithelial-mesenchymal transition (EMT) in the pathogenesis of SNIP remains unclear. EMT marker expression is elevated in SNIP tissues and is associated with its recurrence.

摘要

鼻内翻性乳头状瘤（SNIP）是一种具有高复发率的良性上皮增生性疾病。上皮-间质转化（EMT）在鼻内翻性乳头状瘤发病机制中的作用尚不清楚。EMT标志物在鼻内翻性乳头状瘤组织中的表达升高，且与其复发相关。