Mao Xu, Li Haiyan, Li Xiangxian, Bai Chongbin, Ming Wenjun
School of Information, Yunnan University, Kunming, 650504, China.
School of Information, Yunnan University, Kunming, 650504, China.
Comput Biol Med. 2025 Feb;185:108770. doi: 10.1016/j.compbiomed.2024.108770. Epub 2024 Dec 8.
Colorectal polyps are one of the most direct causes of colorectal cancer. Polypectomy can effectively block the process of colorectal cancer, but accurate polyp segmentation methods are required as an auxiliary means. However, there are several challenges associated with achieving accurate polyp segmentation, such as the large semantic gap between the encoder and decoder, the incomplete edges, and the potential confusion between folds in uncertain areas and target objects. To address the aforementioned challenges, an advanced polyp segmentation network (CE-Net) is proposed, leveraging a cascaded attention mechanism and context-aware cross-level fusion guided by edge learning. Firstly, a cascade attention (CA) module is proposed to capture local feature details and increase the receptive field by setting different dilation rates in different convolutional layers, and combines the criss-cross attention mechanism for bridging the semantic gap between codecs. Subsequently, an edge learning guidance (ELG) module is designed that employs parallel axial attention operations to capture complementary edge information with sufficient detail to enrich feature details and edge features. Ultimately, to effectively integrate cross-level features and obtain rich global contextual information, a context-aware cross-level fusion (CCF) module is introduced through a multi-scale channel attention mechanism to minimize potential confusion between folds in uncertain areas and target objects. A plethora of experimental results has shown that CE-Net is superior over the state-of-the-art methods, with average Dice coefficients on five polyp datasets of 94.54 %, 92.23 %, 82.24 %, 79.53 % and 89.84 %.
结直肠息肉是结直肠癌最直接的病因之一。息肉切除术可以有效阻断结直肠癌的发展进程,但需要精确的息肉分割方法作为辅助手段。然而,实现精确的息肉分割存在若干挑战,例如编码器和解码器之间存在较大的语义鸿沟、边缘不完整以及不确定区域的褶皱与目标物体之间可能产生混淆。为应对上述挑战,提出了一种先进的息肉分割网络(CE-Net),该网络利用级联注意力机制和由边缘学习引导的上下文感知跨层融合。首先,提出了一种级联注意力(CA)模块,通过在不同卷积层设置不同的扩张率来捕捉局部特征细节并扩大感受野,并结合十字交叉注意力机制来弥合编解码器之间的语义鸿沟。随后,设计了一种边缘学习引导(ELG)模块,该模块采用并行轴向注意力操作来捕捉具有足够细节的互补边缘信息,以丰富特征细节和边缘特征。最后,为了有效整合跨层特征并获得丰富的全局上下文信息,通过多尺度通道注意力机制引入了一种上下文感知跨层融合(CCF)模块,以最小化不确定区域的褶皱与目标物体之间的潜在混淆。大量实验结果表明,CE-Net优于现有方法,在五个息肉数据集上的平均Dice系数分别为94.54%、92.23%、82.24%、79.53%和89.84%。