Xiong Yu-Ling, Peng Chao, Deng Ying-Jiang, Li Wei, Huang Yin, Tian Yue
Department of Gastroenterology, Fengdu People's Hospital, Chongqing, China.
Department of Traditional Chinese Medicine and Rheumatology and Immunology, Fengdu People's Hospital, Chongqing, China.
Medicine (Baltimore). 2024 Dec 6;103(49):e40800. doi: 10.1097/MD.0000000000040800.
Antibiotic-associated hemorrhagic colitis (AAHC) is a special type of antibiotic-associated colitis. Due to the increased use of antibiotics, especially amoxicillin, which is commonly used in clinical practice, the incidence of antibiotic-associated hemorrhagic colitis has also increased. However, doctors have insufficient understanding of this disease, and patients may be missed or misdiagnosed.
A 71-year-old female patient was admitted to our hospital with abdominal pain, diarrhea, and bloody stools. There was a history of oral amoxicillin before the onset of the disease.
The final diagnosis of this patient was amoxicillin-associated hemorrhagic colitis.
The patient stopped using antibiotics and was given "Bifidobacterium quadruplex live bacterial tablets and L-glutamine sodium gualenate granules" orally.
After oral administration, the patient's symptom rapidly were completely alleviate. Follow-up colonoscopy revealed normal mucosal images.
Through this case report, doctors should increase their understanding of the disease, especially for patients with sudden abdominal pain accompanied by bloody stools as the main complaint, it is significant to attend to inquiries about the history of antibiotic use, such as amoxicillin, and pay attention to the discovery of acid-producing Klebsiella in the fecal microbiota.
抗生素相关性出血性结肠炎（AAHC）是一种特殊类型的抗生素相关性结肠炎。由于抗生素使用的增加，尤其是临床实践中常用的阿莫西林，抗生素相关性出血性结肠炎的发病率也有所上升。然而，医生对这种疾病的认识不足，患者可能会被漏诊或误诊。
一名71岁女性患者因腹痛、腹泻和便血入院。发病前有口服阿莫西林的病史。
该患者最终诊断为阿莫西林相关性出血性结肠炎。
患者停用抗生素，并口服“双歧杆菌四联活菌片和谷氨酰胺薁磺酸钠颗粒”。
口服后，患者症状迅速完全缓解。随访结肠镜检查显示黏膜图像正常。
通过本病例报告，医生应增加对该疾病的认识，尤其是对于以突发腹痛伴便血为主诉的患者，重视询问抗生素使用史，如阿莫西林，并注意在粪便微生物群中发现产酸克雷伯菌具有重要意义。
