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Pembrolizumab-induced Stevens-Johnson syndrome-like reaction: An atypical clinical presentation.

作者信息

Mahajan Arjun, Chen Ryan, Fischer Grant M, Xiong Yuqing, Ashrafzadeh Sepideh, Said Jordan T, Nambudiri Vinod E

机构信息

Department of Dermatology, Brigham and Women's Hospital, Boston, Massachusetts.

Harvard Medical School, Boston, Massachusetts.

出版信息

JAAD Case Rep. 2024 Oct 28;54:69-72. doi: 10.1016/j.jdcr.2024.10.004. eCollection 2024 Dec.

DOI:10.1016/j.jdcr.2024.10.004
PMID:39654850
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11626045/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6f/11626045/86b05f938d71/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6f/11626045/110be6b3082e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6f/11626045/86b05f938d71/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6f/11626045/110be6b3082e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a6f/11626045/86b05f938d71/gr2.jpg

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本文引用的文献

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Immune checkpoint inhibitor-induced epidermal necrolysis: A narrative review evaluating demographics, clinical features, and culprit medications.免疫检查点抑制剂诱导的表皮坏死松解症:评估人口统计学、临床特征和罪魁祸首药物的叙述性综述。
J Dermatol. 2024 Jan;51(1):3-11. doi: 10.1111/1346-8138.17039. Epub 2023 Nov 30.
2
Management of Immunotherapy-Related Toxicities, Version 1.2022, NCCN Clinical Practice Guidelines in Oncology.免疫治疗相关毒性管理,版本 1.2022,NCCN 肿瘤学临床实践指南。
J Natl Compr Canc Netw. 2022 Apr;20(4):387-405. doi: 10.6004/jnccn.2022.0020.
3
Pembrolizumab-induced Toxic Epidermal Necrolysis in a Patient with Metastatic Esophageal Adenocarcinoma.
帕博利珠单抗诱发的转移性食管腺癌患者中毒性表皮坏死松解症
R I Med J (2013). 2022 Apr 1;105(3):34-36.
4
Generalized bullous mucocutaneous eruption mimicking Stevens-Johnson syndrome in the setting of immune checkpoint inhibition: A multicenter case series.免疫检查点抑制背景下酷似史蒂文斯-约翰逊综合征的泛发性大疱性黏膜皮肤疹:一项多中心病例系列研究
J Am Acad Dermatol. 2020 Nov;83(5):1475-1477. doi: 10.1016/j.jaad.2020.03.029. Epub 2020 Mar 19.
5
The life-threatening eruptions of immune checkpoint inhibitor therapy.免疫检查点抑制剂治疗的危及生命的爆发。
Clin Dermatol. 2020 Jan-Feb;38(1):94-104. doi: 10.1016/j.clindermatol.2019.10.015. Epub 2019 Oct 25.
6
Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis: A Multicenter Retrospective Study of 377 Adult Patients from the United States.史蒂文斯-约翰逊综合征/中毒性表皮坏死松解症:美国 377 例成年患者的多中心回顾性研究。
J Invest Dermatol. 2018 Nov;138(11):2315-2321. doi: 10.1016/j.jid.2018.04.027. Epub 2018 Jul 27.
7
Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis: A Concise Review with a Comprehensive Summary of Therapeutic Interventions Emphasizing Supportive Measures.史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症:一篇简要综述,全面总结治疗干预措施,重点强调支持性措施
Adv Ther. 2017 Jun;34(6):1235-1244. doi: 10.1007/s12325-017-0530-y. Epub 2017 Apr 24.
8
Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies.抗程序性死亡蛋白1(PD-1)和抗程序性死亡配体1(PD-L1)免疫检查点抗体的毒性。
Ann Oncol. 2015 Dec;26(12):2375-91. doi: 10.1093/annonc/mdv383. Epub 2015 Sep 14.
9
ALDEN, an algorithm for assessment of drug causality in Stevens-Johnson Syndrome and toxic epidermal necrolysis: comparison with case-control analysis.ALDEN 算法用于评估 Stevens-Johnson 综合征和中毒性表皮坏死松解症中的药物相关性:与病例对照分析的比较。
Clin Pharmacol Ther. 2010 Jul;88(1):60-8. doi: 10.1038/clpt.2009.252. Epub 2010 Apr 7.
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SCORTEN: a severity-of-illness score for toxic epidermal necrolysis.SCORTEN:一种中毒性表皮坏死松解症的疾病严重程度评分系统。
J Invest Dermatol. 2000 Aug;115(2):149-53. doi: 10.1046/j.1523-1747.2000.00061.x.