Iyer Guhan, Lazar Danielle, Baldridge Abigail S, Mejia Jairo, Chow Clara K, Kandula Namratha R, Sanuade Olutobi A, Rosul Linda, Ciolino Jody D, Huffman Mark D
Cardiovascular Division and Global Health Center, Washington University in St. Louis., St. Louis. MO, USA.
Access Community Health Network, Chicago, IL, USA.
J Clin Transl Sci. 2024 Oct 31;8(1):e187. doi: 10.1017/cts.2024.641. eCollection 2024.
Evaluation of benefits beyond quantitative academic outputs is essential in determining translational research value. We used the Translational Science Benefits Model (TSBM) to examine the impact of the QUARTET USA trial using 30 benefits across 4 domains: Clinical, Community, Economic, and Policy. We found that the QUARTET USA trial demonstrated impact in six areas within the Clinical, and Community domains and had potential impact in two additional areas within the Community and Economic domains. Use of the TSBM supports the value of the QUARTET USA trial, which can be used as a template for future cardiovascular trials.
评估超出定量学术产出的益处对于确定转化研究的价值至关重要。我们使用转化科学益处模型（TSBM），通过4个领域（临床、社区、经济和政策）的30项益处来检验美国四重奏试验的影响。我们发现，美国四重奏试验在临床和社区领域的六个方面显示出影响，在社区和经济领域的另外两个方面具有潜在影响。TSBM的使用支持了美国四重奏试验的价值，该试验可作为未来心血管试验的模板。
