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European Research Council-funded grant: development of a novel cardiac tissue model.

作者信息

Ruocco Gerardina, Testore Daniele, Chiono Valeria

机构信息

Department of Mechanical and Aerospace Engineering, Politecnico di Torino, Corso Duca Degli Abruzzi 24, 10129 Turin, Italy.

Interuniversity Center for the Promotion of the 3Rs Principles in Teaching and Research, Centro 3R, Italy.

出版信息

Eur Heart J. 2025 Jan 16;46(3):233-235. doi: 10.1093/eurheartj/ehae740.

DOI:10.1093/eurheartj/ehae740
PMID:39656453
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7617518/
Abstract
摘要

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本文引用的文献

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2024 Heart Disease and Stroke Statistics: A Report of US and Global Data From the American Heart Association.2024 年心脏病与中风统计数据：美国心脏协会发布的美国和全球数据报告。
Circulation. 2024 Feb 20;149(8):e347-e913. doi: 10.1161/CIR.0000000000001209. Epub 2024 Jan 24.
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Lipoplexes for effective in vitro delivery of microRNAs to adult human cardiac fibroblasts for perspective direct cardiac cell reprogramming.用于将 microRNAs 有效递送至成人人心肌成纤维细胞的脂质体，用于前瞻性的直接心脏细胞重编程。
Nanomedicine. 2022 Sep;45:102589. doi: 10.1016/j.nano.2022.102589. Epub 2022 Jul 28.
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How to Apply Translational Models to Probe Mechanisms of Cardiotoxicity.
如何应用转化模型探究心脏毒性机制。
JACC CardioOncol. 2022 Mar 15;4(1):130-135. doi: 10.1016/j.jaccao.2022.01.097. eCollection 2022 Mar.
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Strategies to apply 3Rs in preclinical testing.在临床前测试中应用 3Rs 的策略。
Pharmacol Res Perspect. 2021 Oct;9(5):e00863. doi: 10.1002/prp2.863.
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Human induced pluripotent stem cell (iPSC)-derived cardiomyocytes as an in vitro model in toxicology: strengths and weaknesses for hazard identification and risk characterization.人诱导多能干细胞（iPSC）衍生的心肌细胞作为毒理学中的体外模型：在危害识别和风险特征描述方面的优势和劣势。
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