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保护最脆弱群体：将受艾滋病病毒影响儿童纳入疟疾化学预防策略的迫切需求。

Protecting the most vulnerable: The urgent need to include HIV-exposed children in malaria chemoprevention strategies.

作者信息

González Raquel, Nhampossa Tacilta, Figueroa-Romero Antía, Tchouatieu André-Marie, Manyando Christine, Menendez Clara

机构信息

ISGlobal, Barcelona, Spain.

Centro de Investigação em Saúde de Manhiça (CISM), Maputo, Mozambique.

出版信息

PLoS Med. 2024 Dec 10;21(12):e1004498. doi: 10.1371/journal.pmed.1004498. eCollection 2024 Dec.

DOI:10.1371/journal.pmed.1004498
PMID:39656683
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11630582/
Abstract

Raquel González and colleagues discuss the drugs available to HIV-exposed children to prevent malaria infection and the urgent need to evaluate alternative agents.

摘要

拉克尔·冈萨雷斯及其同事讨论了可供暴露于艾滋病毒的儿童预防疟疾感染的药物，以及评估替代药物的迫切需求。

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Protecting the most vulnerable: The urgent need to include HIV-exposed children in malaria chemoprevention strategies.保护最脆弱群体：将受艾滋病病毒影响儿童纳入疟疾化学预防策略的迫切需求。
PLoS Med. 2024 Dec 10;21(12):e1004498. doi: 10.1371/journal.pmed.1004498. eCollection 2024 Dec.
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本文引用的文献

1
Uncovering HIV and malaria interactions: the latest evidence and knowledge gaps.揭示 HIV 和疟疾的相互作用：最新证据和知识空白。
Lancet HIV. 2024 Apr;11(4):e255-e267. doi: 10.1016/S2352-3018(24)00035-3. Epub 2024 Mar 5.
2
Chemoprevention for malaria with monthly intermittent preventive treatment with dihydroartemisinin-piperaquine in pregnant women living with HIV on daily co-trimoxazole in Kenya and Malawi: a randomised, double-blind, placebo-controlled trial.在肯尼亚和马拉维，每日服用复方磺胺甲噁唑的 HIV 阳性孕妇中，每月用二氢青蒿素-哌喹进行间歇性预防治疗预防疟疾：一项随机、双盲、安慰剂对照试验。
Lancet. 2024 Jan 27;403(10424):365-378. doi: 10.1016/S0140-6736(23)02631-4. Epub 2024 Jan 12.
3
Safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in pregnant women with HIV from Gabon and Mozambique: a randomised, double-blind, placebo-controlled trial.中-英医学学术文献翻译：来自加蓬和莫桑比克的 HIV 感染孕妇间断性预防治疗应用双氢青蒿素哌喹的安全性和有效性：一项随机、双盲、安慰剂对照试验。
Lancet Infect Dis. 2024 May;24(5):476-487. doi: 10.1016/S1473-3099(23)00738-7. Epub 2024 Jan 12.
4
Drug Interactions between Dolutegravir and Artemether-Lumefantrine or Artesunate-Amodiaquine.多替拉韦与青蒿琥酯-本芴醇或青蒿琥酯-阿莫地喹的药物相互作用。
Antimicrob Agents Chemother. 2019 Jan 29;63(2). doi: 10.1128/AAC.01310-18. Print 2019 Feb.
5
Health and survival of HIV perinatally exposed but uninfected children born to HIV-infected mothers.感染HIV的母亲所生的围产期暴露但未感染HIV儿童的健康与生存情况。
Curr Opin HIV AIDS. 2016 Sep;11(5):465-476. doi: 10.1097/COH.0000000000000300.
6
A Public Health Paradox: The Women Most Vulnerable to Malaria Are the Least Protected.一个公共卫生悖论：最易感染疟疾的女性却受到最少的保护。
PLoS Med. 2016 May 3;13(5):e1002014. doi: 10.1371/journal.pmed.1002014. eCollection 2016 May.
7
Protective efficacy of prolonged co-trimoxazole prophylaxis in HIV-exposed children up to age 4 years for the prevention of malaria in Uganda: a randomised controlled open-label trial.在乌干达，针对预防疟疾，HIV 暴露儿童长达 4 岁时延长复方新诺明预防的保护效果：一项随机对照、开放标签试验。
Lancet Glob Health. 2014 Dec;2(12):e727-36. doi: 10.1016/S2214-109X(14)70329-8.
8
Intermittent preventive treatment of malaria in pregnancy with mefloquine in HIV-infected women receiving cotrimoxazole prophylaxis: a multicenter randomized placebo-controlled trial.在接受复方新诺明预防治疗的感染艾滋病毒的孕妇中，用甲氟喹进行疟疾间歇性预防治疗：一项多中心随机安慰剂对照试验。
PLoS Med. 2014 Sep 23;11(9):e1001735. doi: 10.1371/journal.pmed.1001735. eCollection 2014 Sep.
9
Effectiveness of co-trimoxazole to prevent Plasmodium falciparum malaria in HIV-positive pregnant women in sub-Saharan Africa: an open-label, randomized controlled trial.复方新诺明预防撒哈拉以南非洲地区 HIV 阳性孕妇中恶性疟原虫疟疾的效果：一项开放标签、随机对照试验。
Clin Infect Dis. 2014 Mar;58(5):651-9. doi: 10.1093/cid/cit806. Epub 2013 Dec 12.
10
Health outcomes of HIV-exposed uninfected African infants.HIV 暴露但未感染的非洲婴儿的健康结果。
AIDS. 2013 Mar 13;27(5):749-59. doi: 10.1097/QAD.0b013e32835ca29f.