五岁以下因重度急性营养不良住院的马拉维儿童的感染与抗生素耐药性
Infections and Antibiotic Resistance in Malawian Children Under Five-Years Old Hospitalized With Severe Acute Malnutrition.
作者信息
Vonasek Bryan J, Nyirongo Mwawi, Kondwani Alexander, Kamvaunamwali Tiwonge, Ng'oma Doris, Ciccone Emily J, Kaphatika James, Tepeka Amazing-Grace, Kumwenda Mercy, Eickhoff Jens, Garcia-Prats Anthony J, Mvalo Tisungane
机构信息
Department of Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin, USA.
Department of Paediatrics and Child Health, Kamuzu Central Hospital, Lilongwe, Malawi.
出版信息
J Pediatric Infect Dis Soc. 2025 Jan 20;14(1). doi: 10.1093/jpids/piae120.
Abstract
This prospective cohort study from Malawi updates our understanding of the burden of bacterial infections and drug resistance in children <5 years hospitalized with severe acute malnutrition. Urinary tract infection was diagnosed in 20% and bacteremia in 10%. Resistance to first- and second-line antibiotics occurred in >1/3 of the bacteria isolated.
摘要
这项来自马拉维的前瞻性队列研究更新了我们对患有重度急性营养不良的5岁以下住院儿童细菌感染负担和耐药性的认识。20%的患儿被诊断出患有尿路感染，10%的患儿患有菌血症。分离出的细菌中超过三分之一对一线和二线抗生素耐药。
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