ElSherif Mayada, Fathey El Sayed Mahfouz Aya, Mohamed Gaber Amin Noha, Saad Kozou Hesham
Department of Otorhinolaryngology, Audiovestibular Medicine Unit, Alexandria University Faculty of Medicine, Alexandria, Egypt.
Department of Internal Medicine, Alexandria University Faculty of Medicine, Alexandria, Egypt.
J Int Adv Otol. 2024 Nov 25;20(6):531-535. doi: 10.5152/iao.2024.241615.
Glycemic control and the efficacy of therapy in diabetic patients with type 2 diabetes during the previous 2-3 months are usually evaluated by measuring the glycated hemoglobin (HbA1c). Our aim is to study the correlation between serum glycated hemoglobin level (HbA1c) and the hearing thresholds in diabetic patients.
A case-control study was conducted in the Audio-Vestibular Medicine Unit, xxxx University on 82 subjects. The subjects were divided into 2 groups: the first group consisted of 42 diabetic patients and the second group consisted of 40 healthy subjects. All the participants underwent a pure tone audiogram and speech audiometric evaluation. All participants also underwent diabetes laboratory assessments, including fasting blood glucose serum level and serum HbA1c level. The average hearing threshold at frequencies from 250 Hz to 16 000 Hz in both groups was calculated and correlated to different variables.
Diabetic patients showed higher hearing thresholds than those of the control group, with an increasing tendency of elevation of the hearing threshold levels toward the higher frequencies in both groups. There was no statistically significant difference in the hearing thresholds between patients with diabetes < 5 years (20 subjects) and those with a duration of ≤ 5 years (22 subjects). Also, there was no statistically significant difference in the average hearing thresholds among type 2 diabetic patients based on fasting blood sugar level results, except at 16 000 Hz.
Poor glycemic control status [Hb A1c ≥ 7%] is significantly associated with elevated hearing thresholds.
通常通过测量糖化血红蛋白（HbA1c）来评估2型糖尿病患者在过去2 - 3个月的血糖控制情况及治疗效果。我们的目的是研究糖尿病患者血清糖化血红蛋白水平（HbA1c）与听力阈值之间的相关性。
在xxxx大学听觉前庭医学科对82名受试者进行了一项病例对照研究。受试者分为两组：第一组由42名糖尿病患者组成，第二组由40名健康受试者组成。所有参与者均接受了纯音听力图和言语听力评估。所有参与者还进行了糖尿病实验室评估，包括空腹血糖血清水平和血清HbA1c水平。计算两组在250Hz至16000Hz频率范围内的平均听力阈值，并将其与不同变量进行相关性分析。
糖尿病患者的听力阈值高于对照组，且两组的听力阈值水平均有随频率升高而升高的趋势。糖尿病病程<5年的患者（20名）与病程≤5年的患者（22名）之间的听力阈值无统计学显著差异。此外，根据空腹血糖水平结果，2型糖尿病患者的平均听力阈值在除16000Hz外无统计学显著差异。
血糖控制不佳状态[Hb A1c≥7%]与听力阈值升高显著相关。
