Maimaitiaishan Tangnuer, Wang Xiaobing, Chen Xiaojia, Zhou Feng, Ding Feng, Cheng Jie, Lin Jun, Chen Liping
Department of Gastroenterology and Hepatology, Zhongnan Hospital of Wuhan University, No. 169, Donghu Road, Wuchang District, Wuhan, 430071, Hubei Province, China.
Hubei Clinical Center & Key Lab of Intestinal & Colorectal Diseases, Wuhan, China.
Cardiovasc Intervent Radiol. 2025 Jan;48(1):102-107. doi: 10.1007/s00270-024-03932-5. Epub 2024 Dec 11.
This study aimed to explore a modified direct intrahepatic portocaval shunt (DIPS) technique as an alternative approach for patients with portal vein occlusion (PVO) and cirrhosis who were not candidates for traditional transjugular intrahepatic portosystemic shunt (TIPS) due to anatomical challenges.
Three patients with esophageal or gastric fundus variceal hemorrhage complicated by severe PVO were treated using innovative DIPS approaches. Preoperative contrast-enhanced computed tomography was employed to assess anatomical feasibility. The modified DIPS techniques involved targeting dilated varicose veins or the confluence of the superior mesenteric and splenic veins to access the inferior vena cava. For broader clinical applications, we outlined the anatomical conditions necessary for adopting the method proposed in this study. Following the puncture, portal hypertension was effectively alleviated, and bleeding was controlled. There were no obvious complications during the follow-up period.
Modified DIPS targeting different vessels appears to be a feasible alternative for the treatment of severe PVO when conventional TIPS by ultrasound-guided percutaneous transhepatic or transsplenic pathway and DIPS are unsuccessful. Future validation in a larger patient population is needed.
Level 4, Case Series.
本研究旨在探索一种改良的直接肝内门体分流术(DIPS)技术,作为门静脉闭塞(PVO)和肝硬化患者的另一种治疗方法,这些患者因解剖结构复杂而不适合传统的经颈静脉肝内门体分流术(TIPS)。
采用创新的DIPS方法治疗3例食管或胃底静脉曲张破裂出血合并严重PVO的患者。术前采用对比增强计算机断层扫描评估解剖学可行性。改良的DIPS技术包括将扩张的静脉曲张或肠系膜上静脉与脾静脉的汇合处作为靶点,以进入下腔静脉。为了更广泛的临床应用,我们概述了采用本研究中提出的方法所需的解剖学条件。穿刺后,门静脉高压得到有效缓解,出血得到控制。随访期间无明显并发症。
当超声引导下经皮经肝或经脾途径的传统TIPS和DIPS均失败时,针对不同血管的改良DIPS似乎是治疗严重PVO的一种可行替代方法。未来需要在更大规模的患者群体中进行验证。
4级,病例系列。