Use of Hyaluronic Acid Hybrid Complex to Treat Wrinkles in the Upper Third of the Face: A Case Report.

Physical changes, such as skin atrophy, loss of elasticity, and the appearance of fine lines and wrinkles, are common during aging. A hybrid hyaluronic acid (HA) complex containing both low and high molecular weight has shown promising results in promoting skin restructuring by remodeling the epidermis, dermis, and hypodermis. This study describes three cases of facial aging, each with unique challenges. The upper third of the face was treated with two sessions spaced 30 days apart of hybrid HA using the blanching technique. These cases highlight the pressing need for alternative treatments that regenerate new tissues and cells, leading to a new skin architecture, as the use of neuromodulators in isolation can lead to unwanted side effects. The recovery of extracellular matrix proteins in this region with hybrid HA has significantly improved the elasticity, firmness, texture, and hydration of the skin, providing a healthier appearance and reducing the quantity and depth of facial wrinkles.