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病例报告:急性缺血性脑干卒中后吉兰-巴雷综合征

Case report: Guillain-Barré syndrome following acute ischemic brainstem stroke.

作者信息

Xu Da, Yu Cheng, Deng Xue-Jun, Li Man

机构信息

Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.

出版信息

Front Immunol. 2024 Nov 27;15:1403561. doi: 10.3389/fimmu.2024.1403561. eCollection 2024.

Abstract

Guillain-Barré syndrome (GBS) is a heterogeneous disease, and it usually develops after an antecedent infection, while rare cases develop following a central nervous system disease. Given the indeterminacy of prodromal infection symptoms and the overlap of symptoms with other neurological disorders, a rigorous clinical and neurological examination in conjunction with history is necessary for early diagnosis and treatment of GBS. Here we present a rare case of GBS following acute ischemic stroke which was different from previous reports such as GBS following hemorrhagic stroke or head trauma. Moreover, intravenous immunoglobulin was effective in this patient after 6 months of follow-up despite the potential risk of thrombotic events.

摘要

吉兰-巴雷综合征(GBS)是一种异质性疾病,通常在先前感染后发病,而罕见病例在中枢神经系统疾病后发生。鉴于前驱感染症状的不确定性以及与其他神经系统疾病症状的重叠,结合病史进行严格的临床和神经学检查对于GBS的早期诊断和治疗至关重要。在此,我们报告一例罕见的急性缺血性卒中后发生GBS的病例,该病例与先前报道的如出血性卒中或头部外伤后发生GBS的病例不同。此外,尽管存在血栓形成事件的潜在风险,但在随访6个月后,静脉注射免疫球蛋白对该患者有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/cf09/11631871/e1588a4f6343/fimmu-15-1403561-g001.jpg

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