胃和眼眶黏膜相关淋巴组织淋巴瘤同时出现：一例报告

Mirzaee Elahe, Garousi Maryam, Jafari Shima, Soltani Sepideh, Rakhshani Nasser, Abdi Navid, Fadavi Pedram

Department of Radiation Oncology, School of Medicine Iran University of Medical Sciences Tehran Iran.

Gastrointestinal and Liver Diseases Research Center, Firoozgar Hospital Iran University of Medical Sciences Tehran Iran.

Clin Case Rep. 2024 Dec 10;12(12):e9712. doi: 10.1002/ccr3.9712. eCollection 2024 Dec.

Mucosa-associated lymphoid tissue lymphoma or MALToma occurs in 8% of B-cell non-Hodgkin lymphoma according to the latest WHO classification. The most involved site of MALToma is stomach. We describe a rare case of concurrent gastric and orbital mucosa-associated lymphoid tissue lymphoma (MALToma) of a female who presented with progressive proptosis and abdominal pain. We performed six courses of chemotherapy (Rituximab) and gastric and orbital radiation with a dose of 34 Gy/20 Fr and 30 Gy/20 Fr, respectively. This case underscores the efficacy of a multimodal treatment strategy in achieving successful outcomes.

根据世界卫生组织的最新分类，黏膜相关淋巴组织淋巴瘤（MALToma）占B细胞非霍奇金淋巴瘤的8%。MALToma最常累及的部位是胃。我们描述了一例罕见的女性同时发生胃和眼眶黏膜相关淋巴组织淋巴瘤（MALToma）的病例，该患者表现为进行性眼球突出和腹痛。我们进行了六个疗程的化疗（利妥昔单抗），并分别对胃和眼眶进行了放疗，剂量分别为34 Gy/20次和30 Gy/20次。该病例强调了多模式治疗策略在取得成功结果方面的有效性。