Bhamare Shruti A, Dahake Prasanna T, Kale Yogesh J, Dadpe Mahesh V, Kendre Shrikant B
Department of Pedodontics and Preventive Dentistry, Maharashtra Institute of Dental Sciences and Research (MIDSR), Latur, Maharashtra, India.
Int J Clin Pediatr Dent. 2024 Sep;17(9):1004-1013. doi: 10.5005/jp-journals-10005-2922.
has a pathogenic role in failed endodontic treatments. The study aimed to assess the efficiency of (SA) and cinnamon oil (CO) extract on biofilm eradication.
The antibacterial efficacy of SA and CO against was assessed by the tests of minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC), and further, the interaction with agents was evaluated at different time intervals by a time-kill assay. The inhibition efficacy of both agents was determined by biofilm adhesion reduction crystal violet assay.
The MIC of SA was 25 μg/mL, and for CO, it was 12.5 μg/mL. The time-kill assay revealed that antibacterial efficacy was identified till 36 hours by both the test materials. The mean biofilm reduction at 25 µg/mL of calcium hydroxide [Ca(OH)], SA, and CO was 1.53 ± 0.05, 1.83 ± 1.57, and 2.06 ± 0.05, respectively.
SA and CO demonstrated promising antibacterial efficacy against and CO presented significant eradication of biofilms compared to SA.
Bhamare SA, Dahake PT, Kale YJ, Effect of Herbal Extract of and Cinnamon Oil on Biofilm Eradication: An Study. Int J Clin Pediatr Dent 2024;17(9):1004-1013.
在根管治疗失败中具有致病作用。本研究旨在评估[具体植物名称]（SA）和肉桂油（CO）提取物对[具体细菌名称]生物膜根除的效果。
通过最低抑菌浓度（MIC）和最低杀菌浓度（MBC）测试评估SA和CO对[具体细菌名称]的抗菌效果，此外，通过时间杀菌试验在不同时间间隔评估与药物的相互作用。两种药物的抑制效果通过生物膜黏附减少结晶紫试验确定。
SA的MIC为25μg/mL，CO的MIC为12.5μg/mL。时间杀菌试验显示两种测试材料的抗菌效果在36小时内均可识别。在25μg/mL的氢氧化钙[Ca(OH)]、SA和CO作用下，生物膜平均减少量分别为1.53±0.05、1.83±1.57和2.06±0.05。
SA和CO对[具体细菌名称]显示出有前景的抗菌效果，且与SA相比，CO对生物膜有显著的根除作用。
Bhamare SA, Dahake PT, Kale YJ, [具体植物名称]和肉桂油的草药提取物对[具体细菌名称]生物膜根除的影响：一项[具体研究类型]研究。《国际临床儿科牙科学杂志》2024年；17(9):1004 - 1013。
