[具体物质名称]对烧伤的治疗作用。 （原文中“in Burn Injuries”前缺少具体物质，这里补充了[具体物质名称]以使译文完整通顺）
Healing Effect of in Burn Injuries.
作者信息
Hamedi Zahra Sadat, Manafi Amir, Hashemi Seyedeh-Sara, Mehrabani Davood, Seddighi Anahita, Tanideh Nader, Mokhtari Maral
机构信息
Division of Hematology, Oncology and Palliative Care, Department of Internal Medicine, Virginia Commonwealth University Health System, Richmond, Virginia.
Department of Anesthesiology, Arrowhead Regional Medical Center, Colton, California.
出版信息
World J Plast Surg. 2024;13(3):57-65. doi: 10.61186/wjps.13.3.57.
BACKGROUND
Burn injury is still the leading cause of mortality and morbidity in burn patients. We comapred healing effect of , silver sulfadiazine and alpha ointments on burn injuries in rat model.
METHODS
Sixty female Sprague-Dawley rats in an animal experimental study were randomly divided to 5 equal groups as , silver sulfadiazine and (SSD), alpha, gel base and the burn injury left untreated. Wounds were assessed macroscopically and histologic after burn injury and on days 7, 14 and 21 after treatments.
RESULTS
Burn wounds decreased in size on day 7 in group (<0.01). Regarding scoring the inflammation, re-epithelialization, angiogenesis, formation of granulation tissue and number of macrophage, the best scores were visible in group, and the worst in the gel base and the burn injury left untreated (<0.01).
CONCLUSIONS
was shown to significantly induce re-epithelialization, angiogenesis and granulation tissue and decrease the inflammation resulting into a healing process in burn wounds. As is inexpensive and an easily available herbal medicine, it can be considered as a therapeutic of choice to ameliorate burn injuries.
背景
烧伤仍是烧伤患者死亡和发病的主要原因。我们比较了[未提及药物名称]、磺胺嘧啶银和α软膏对大鼠烧伤模型的愈合效果。
方法
在一项动物实验研究中，将60只雌性斯普拉格-道利大鼠随机分为5组，每组数量相等，分别为[未提及药物名称]组、磺胺嘧啶银（SSD）组、α组、凝胶基质组和未治疗的烧伤组。在烧伤后以及治疗后第7天、14天和21天，对伤口进行宏观和组织学评估。
结果
[未提及药物名称]组烧伤创面在第7天时面积减小（<0.01）。在炎症、再上皮化、血管生成、肉芽组织形成和巨噬细胞数量评分方面，[未提及药物名称]组得分最佳，凝胶基质组和未治疗的烧伤组得分最差（<0.01）。
结论
[未提及药物名称]被证明能显著诱导再上皮化、血管生成和肉芽组织形成，并减轻炎症，从而促进烧伤创面的愈合过程。由于[未提及药物名称]价格低廉且是一种易于获得的草药，它可被视为改善烧伤的首选治疗药物。
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