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[具体物质名称]与姜黄素对大鼠烧伤创面愈合作用的评估

Evaluation of the Healing Effects of and Curcumin on Burn Wounds in Rats.

作者信息

Seyhan Nevra

机构信息

Department of Plastic Reconstructive, Aesthetic Surgery Gulhane Education and Research Hospital, Ankara, Turkey.

出版信息

Evid Based Complement Alternat Med. 2020 Feb 13;2020:6462956. doi: 10.1155/2020/6462956. eCollection 2020.

Abstract

BACKGROUND

For centuries, medicinal plants have been extensively used in wound healing of burn injuries. The aim of this study is to analyze comparatively the effects of curcumin and (HP) on second-degree burn wounds in rats. . This experimental study was conducted on 24 male Sprague-Dawley rats with second-degree burns. The animals were randomly divided into three groups. The burns were treated with curcumin (Group B) and (HP) on second-degree burn wounds in rats.

RESULTS

All histological parameters of the control group showed statistically significant difference than the other groups ( < 0.05). There was no statistically significant difference between Groups B and C in terms of reepithelization and inflammation ( < 0.05). There was no statistically significant difference between Groups B and C in terms of reepithelization and inflammation ( < 0.05). There was no statistically significant difference between Groups B and C in terms of reepithelization and inflammation ( < 0.05). There was no statistically significant difference between Groups B and C in terms of reepithelization and inflammation (.

CONCLUSION

Both curcumin and oil are effective in burn wound healing. Our findings showed a better quality of healing in curcumin-treated rats. (HP) on second-degree burn wounds in rats.

摘要

背景

几个世纪以来,药用植物一直被广泛用于烧伤创面的愈合。本研究的目的是比较姜黄素和(HP)对大鼠二度烧伤创面的影响。本实验研究对24只雄性Sprague-Dawley大鼠进行二度烧伤。动物被随机分为三组。对大鼠的二度烧伤创面用姜黄素(B组)和(HP)进行治疗。

结果

对照组的所有组织学参数与其他组相比均有统计学显著差异(<0.05)。B组和C组在再上皮化和炎症方面无统计学显著差异(<0.05)。B组和C组在再上皮化和炎症方面无统计学显著差异(<0.05)。B组和C组在再上皮化和炎症方面无统计学显著差异(<0.05)。B组和C组在再上皮化和炎症方面无统计学显著差异(。

结论

姜黄素和油对烧伤创面愈合均有效。我们的研究结果显示,姜黄素治疗的大鼠愈合质量更好。(HP)对大鼠二度烧伤创面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f6a4/7042516/d2629cdb0e4b/ECAM2020-6462956.001.jpg

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