MacIntyre Olivia C, Purdy Kerri
Faculty of Medicine, Dalhousie University, Halifax, NS, Canada.
Division of Clinical Dermatology and Cutaneous Science, Department of Medicine, Dalhousie University, Halifax, NS, Canada.
SAGE Open Med Case Rep. 2024 Dec 11;12:2050313X241304954. doi: 10.1177/2050313X241304954. eCollection 2024.
A 56-year-old male presented to the clinic for follow-up of severe, longstanding hidradenitis suppurativa. On physical examination, there was a linear Blaschkoid distribution of erythematous scaly papules extending from the left upper arm toward the scapular mid-back region. A clinical diagnosis of linear psoriasis was made, and the patient's dosage interval of infliximab was decreased to every 6 weeks. The patient was offered Betamethasone diproprionate/calcipotriol (Enstilar) topical foam to use daily which demonstrated efficacy in clearing 90% of the affected areas. This case illustrates the potential for Betamethasone diproprionate/calcipotriol (Enstilar) topical foam use as a treatment approach for anti-tumor necrosis factor-alpha inhibitor-induced linear psoriasis. At present there is no consensus on linear psoriasis pathogenesis or best treatment approach, therefore, more research is needed to understand its pathogenesis and establish management guidelines.
一名56岁男性因严重、长期的化脓性汗腺炎前来诊所复诊。体格检查发现，从左上臂向肩胛中背部区域延伸有一条呈Blaschkoid分布的红斑鳞屑性丘疹线。临床诊断为线状银屑病，患者英夫利昔单抗的给药间隔缩短至每6周一次。为患者提供了丙酸倍他米松/卡泊三醇（恩斯梯拉）外用泡沫剂，建议每日使用，该药物在清除90%的受累区域方面显示出疗效。该病例说明了丙酸倍他米松/卡泊三醇（恩斯梯拉）外用泡沫剂作为抗肿瘤坏死因子-α抑制剂诱导的线状银屑病治疗方法的潜力。目前，关于线状银屑病的发病机制或最佳治疗方法尚无共识，因此，需要更多的研究来了解其发病机制并制定管理指南。
