幼犬牙髓对部分牙髓切断术与完全牙髓切断术的反应：一项实验研究。
Pulpal response to partial pulpotomy versus full pulpotomy procedures in puppies: An experimental study.
作者信息
AlDhelai Thiyezen Abdullah, Alsughier Zeyad, Alotaiby Faraj, Alattas Mustafa Hussein, Javed Muhammad Qasim, Sadan Madeh, Salem Rania M, Elkateb Mona A
机构信息
Department of Orthodontic and Pediatric Dentistry, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.
Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, Qassim University, Buraydah, Saudi Arabia.
出版信息
PLoS One. 2024 Dec 12;19(12):e0312076. doi: 10.1371/journal.pone.0312076. eCollection 2024.
BACKGROUND
A Partial pulpotomy technique is an alternative choice of treatment for immature permanent teeth with exposed vital pulps. This study aimed to compare the histopathological pulpal response of the primary teeth of puppies after partial pulpotomy and full pulpotomy using mineral trioxide aggregate (MTA).
MATERIALS AND METHODS
72 primary premolars from experimental puppies aged 6-8 weeks were equally divided into test and control groups, as MTA partial pulpotomy (MTA-PP) and MTA full pulpotomy (MTA-FP). After 60 days, the teeth were extracted and examined histologically. The specimens were assessing the extent and intensity of inflammatory response (acute or chronic), necrosis, fibrosis, calcific bridge (presence or absence), pulp calcification, and pathological root resorption.
RESULTS
The Inflammation intensity was lower (2.8%) in MTA-PP than in MTA-FP (16.7%) (P = 0.004). MTA-FP also had a significantly higher percentage of localized (27.8%) and diffuse (11.1%) necrosis (P = 0.014), whereas both groups (P = 0.290) had an equal fibrosis degree. A calcific bridge was observed in 72.2% of cases. Meanwhile, pathological internal root resorption was more evident in MTA-FP (63.9%) than in MTA-PP (19.4%) (P <0.0001).
CONCLUSION
Partial MTA pulpotomy procedure demonstrated promising histological findings that can be applied to vital-pulp therapy in primary teeth.
背景
部分牙髓切断术是治疗牙髓暴露的年轻恒牙的一种替代治疗选择。本研究旨在比较使用三氧化矿物凝聚体（MTA）进行部分牙髓切断术和完全牙髓切断术后幼犬乳牙的组织病理学牙髓反应。
材料与方法
将72颗来自6 - 8周龄实验幼犬的乳前磨牙平均分为试验组和对照组，即MTA部分牙髓切断术（MTA - PP）组和MTA完全牙髓切断术（MTA - FP）组。60天后，拔除牙齿并进行组织学检查。对标本评估炎症反应（急性或慢性）的程度和强度、坏死、纤维化、钙化桥（存在或不存在）、牙髓钙化和病理性牙根吸收情况。
结果
MTA - PP组的炎症强度（2.8%）低于MTA - FP组（16.7%）（P = 0.004）。MTA - FP组局部（27.8%）和弥漫性（11.1%）坏死的百分比也显著更高（P = 0.014），而两组的纤维化程度相同（P = 0.290）。72.2%的病例观察到钙化桥。同时，MTA - FP组（63.9%）的病理性牙根内吸收比MTA - PP组（19.4%）更明显（P <0.0001）。
结论
MTA部分牙髓切断术显示出有前景的组织学结果，可应用于乳牙的活髓治疗。
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