Zhou Binbin, Li Xinyi, Xie Hao, Sheng Xingxin, Huang Lijun, Zhu Yongbo, Liang Meng, Zhong Ming
College of Chemistry and Chemical Engineering, Hunan Institute of Science and Technology, Yueyang, 414006, Hunan, China.
Mikrochim Acta. 2024 Dec 13;192(1):14. doi: 10.1007/s00604-024-06858-4.
A novel molecular-imprinted electrochemical sensor for 3,4-benzopyrene (3, 4-BaP) in food samples, with high sensitivity and selective detection, is introduced. Firstly, graphene oxide was modified onto a glassy carbon electrode (GCE) by electroreduction deposition to form an RGO/GCE sensing platform, thereby enhancing the sensitivity and stability of the sensor. Then, magnetic molecularly imprinted polymer-zeolite imidazole framework-8 (MMIP-ZIF-8) was synthesized in one step using the crystal growth method and modified onto RGO/GCE, endowing the sensor with good adsorption capacity and selectivity. The performance of the sensor for 3, 4-BaP was studied using differential pulse voltammetry (DPV), and the detection conditions of the constructed sensor were optimized. The results showed that under the optimal conditions, the constructed sensor exhibited a wide linear range (0.5 ~ 1000 nmol L), a low limit of detection (0.16 nmol L), and good selectivity and stability for the detection of 3, 4-BaP. It also showed a good recovery (99.74 ~ 102.58%) for the detection of 3, 4-BaP in actual corn meal samples. The MMIP-ZIF-8/RGO/GCE sensor developed has potential application prospects in the precise detection of 3, 4-BaP in food.
介绍了一种用于食品样品中3,4-苯并芘（3,4-BaP）的新型分子印迹电化学传感器，具有高灵敏度和选择性检测能力。首先，通过电还原沉积将氧化石墨烯修饰在玻碳电极（GCE）上，形成RGO/GCE传感平台，从而提高传感器的灵敏度和稳定性。然后，采用晶体生长法一步合成磁性分子印迹聚合物-沸石咪唑框架-8（MMIP-ZIF-8）并修饰在RGO/GCE上，赋予传感器良好的吸附能力和选择性。利用差分脉冲伏安法（DPV）研究了该传感器对3,4-BaP的性能，并对构建的传感器的检测条件进行了优化。结果表明，在最佳条件下，构建的传感器对3,4-BaP检测具有宽线性范围（0.5～1000 nmol/L）、低检测限（0.16 nmol/L）以及良好的选择性和稳定性。在实际玉米粉样品中检测3,4-BaP时，回收率也良好（99.74～102.58%）。所研制的MMIP-ZIF-8/RGO/GCE传感器在食品中3,4-BaP的精确检测方面具有潜在的应用前景。
