Shi Chenyang, Zhu Donglin, Zhou Changjun, Cheng Shi, Zou Chengye
School of Computer Science and Technology, Zhejiang Normal University, Jinhua, 321004 China.
School of Computer Science, Shaanxi Normal University, Xi'an, 710119 China.
Health Inf Sci Syst. 2024 Mar 11;12(1):24. doi: 10.1007/s13755-024-00285-8. eCollection 2024 Dec.
In the field of biomedical science, blood cell detection in microscopic images is crucial for aiding physicians in diagnosing blood-related diseases and plays a pivotal role in advancing medicine toward more precise and efficient treatment directions. Addressing the time-consuming and error-prone issues of traditional manual detection methods, as well as the challenge existing blood cell detection technologies face in meeting both high accuracy and real-time requirements, this study proposes a lightweight blood cell detection model based on YOLOv8n, named GPMB-YOLO. This model utilizes advanced lightweight strategies and PGhostC2f design, effectively reducing model complexity and enhancing detection speed. The integration of the simple parameter-free attention mechanism (SimAM) significantly enhances the model's feature extraction ability. Furthermore, we have designed a multidimensional attention-enhanced bidirectional feature pyramid network structure, MCA-BiFPN, optimizing the effect of multi-scale feature fusion. And use genetic algorithms for hyperparameter optimization, further improving detection accuracy. Experimental results validate the effectiveness of the GPMB-YOLO model, which realized a 3.2% increase in mean Average Precision (mAP) compared to the baseline YOLOv8n model and a marked reduction in model complexity. Furthermore, we have developed a blood cell detection system and deployed the model for application. This study serves as a valuable reference for the efficient detection of blood cells in medical images.
在生物医学科学领域,显微图像中的血细胞检测对于帮助医生诊断血液相关疾病至关重要,并且在推动医学朝着更精确、高效的治疗方向发展方面发挥着关键作用。针对传统人工检测方法耗时且容易出错的问题,以及现有血细胞检测技术在满足高精度和实时性要求方面面临的挑战,本研究提出了一种基于YOLOv8n的轻量级血细胞检测模型,名为GPMB - YOLO。该模型采用先进的轻量级策略和PGhostC2f设计,有效降低了模型复杂度并提高了检测速度。简单无参数注意力机制(SimAM)的集成显著增强了模型的特征提取能力。此外,我们设计了一种多维注意力增强双向特征金字塔网络结构MCA - BiFPN,优化了多尺度特征融合的效果。并使用遗传算法进行超参数优化,进一步提高检测精度。实验结果验证了GPMB - YOLO模型的有效性,与基线YOLOv8n模型相比,其平均精度均值(mAP)提高了3.2%,且模型复杂度显著降低。此外,我们开发了一个血细胞检测系统并将该模型进行了应用部署。本研究为医学图像中血细胞的高效检测提供了有价值的参考。