Costanzo-Nordin M R, O'Connell J B, Subramanian R, Robinson J A, Scanlon P J
Br Heart J. 1985 Jan;53(1):25-9. doi: 10.1136/hrt.53.1.25.
Two cases of acute myocardial infarction occurred in association with myocarditis, which was confirmed by biopsy. The first patient suffered an anteroseptal and the second patient an inferior wall myocardial infarction shortly after an acute viral illness. In both patients, coronary angiography showed normal coronary arteries, and right ventricular endomyocardial biopsy confirmed myocarditis. Histological abnormalities attributable to ischaemic heart disease were absent. The first patient's condition became stable after immunosuppressive treatment. Myocarditis resolved spontaneously within three months in the second patient. Coronary artery spasm and myocardial involvement with a systemic disease were unlikely. Endomyocardial biopsy in patients with acute myocardial infarction and normal coronary arteries may be useful in identifying myocarditis associated with myocardial necrosis. Myocarditis in acute myocardial infarction in the absence of coronary artery obstruction has not previously been documented during life.
有两例急性心肌梗死与心肌炎相关，经活检确诊。首例患者在急性病毒感染疾病后不久发生前间隔心肌梗死，第二例患者发生下壁心肌梗死。两名患者冠状动脉造影均显示冠状动脉正常，右心室心内膜活检确诊为心肌炎。未发现缺血性心脏病所致的组织学异常。首例患者经免疫抑制治疗后病情稳定。第二例患者的心肌炎在三个月内自发缓解。冠状动脉痉挛和心肌受累伴全身性疾病的可能性不大。急性心肌梗死且冠状动脉正常的患者进行心内膜活检，可能有助于识别与心肌坏死相关的心肌炎。此前尚无在急性心肌梗死且无冠状动脉阻塞情况下发生心肌炎的生前记录。
