Murakami Aito, Watanabe-Yanai Ayako, Iwata Taketoshi, Namai Fu, Sato Takashi, Fujii Tadashi, Tochio Takumi, Khempaka Sutisa, Shimosato Takeshi
Graduate School of Medicine, Science and Technology, Shinshu University, Nagano, Japan.
Division of Zoonosis Research, National Institute of Animal Health, National Agriculture and Food Research Organization, Tsukuba, Japan.
Front Microbiol. 2024 Nov 28;15:1491039. doi: 10.3389/fmicb.2024.1491039. eCollection 2024.
As the global population continues to grow, so too does the demand for poultry meat. However, the concurrent increase in the prevalence of drug-resistant bacteria has stimulated interest in the search for alternatives to antibiotics in poultry and livestock agriculture. One potential strategy is the use of probiotics. In this study, we showed that prophylactic oral administration of C37 (LIC37) reduced colonization of the cecum in cage-raised chicks, without causing significant changes in the overall diversity of gut bacteria. Further, the abundance of , another genus of probiotic bacteria, increased in the gastrointestinal tract following ingestion of LIC37 by chicks. These findings suggest that LIC37 could potentially be used as a novel probiotic agent against in livestock production.
随着全球人口持续增长，对禽肉的需求也在增加。然而，耐药菌患病率的同时上升激发了人们对在家禽和家畜养殖中寻找抗生素替代品的兴趣。一种潜在策略是使用益生菌。在本研究中，我们表明预防性口服C37（LIC37）可减少笼养雏鸡盲肠的定植，而不会导致肠道细菌的总体多样性发生显著变化。此外，雏鸡摄入LIC37后，另一种益生菌属在胃肠道中的丰度增加。这些发现表明，LIC37有可能作为一种新型益生菌剂用于家畜生产中对抗（此处原文缺失相关细菌名称）。
