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髂骨骨内血管瘤:一例酷似转移性疾病的偶然发现。

Intraosseous Hemangioma of the Iliac Bone: An Incidental Finding Mimicking Metastatic Disease.

作者信息

Louis Mena, Hayden Anna, Grabill Nathaniel, Strom Priscilla

机构信息

General Surgery, Northeast Georgia Medical Center Gainesville, Gainesville, USA.

出版信息

Cureus. 2024 Nov 12;16(11):e73523. doi: 10.7759/cureus.73523. eCollection 2024 Nov.

DOI:10.7759/cureus.73523
PMID:39669857
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11636397/
Abstract

Intraosseous hemangiomas are rare benign vascular tumors predominantly occurring in the axial skeleton. This case report describes a 44-year-old female with a history of multiple renal stones and benign breast calcifications, who was incidentally found to have a 1.2 cm lucent lesion in the left iliac bone during imaging for nephrolithiasis. Initial concerns for metastatic disease prompted further evaluation, including bone scans and multiple biopsies. The first biopsy revealed benign bone tissue with blood elements, while a subsequent computed tomography (CT)-guided biopsy confirmed the diagnosis of an intraosseous hemangioma through the identification of benign vascular elements and adipose tissue, supported by positive immunohistochemical staining for CD34 and CD31. Accurate diagnosis relies on comprehensive imaging and histopathological evaluation to differentiate them from malignant lesions. Correct identification prevents unnecessary surgical interventions and minimizes associated risks. Conservative management is generally effective for asymptomatic cases, ensuring positive patient outcomes.

摘要

骨内血管瘤是一种罕见的良性血管肿瘤,主要发生于中轴骨骼。本病例报告描述了一名44岁女性,有多次肾结石和乳腺良性钙化病史,在因肾结石进行影像学检查时偶然发现左髂骨有一个1.2 cm的透亮病变。最初对转移性疾病的担忧促使进一步评估,包括骨扫描和多次活检。第一次活检显示为含有血液成分的良性骨组织,而随后的计算机断层扫描(CT)引导下活检通过识别良性血管成分和脂肪组织,以及CD34和CD31免疫组化染色阳性,确诊为骨内血管瘤。准确的诊断依赖于全面的影像学和组织病理学评估,以将它们与恶性病变区分开来。正确识别可避免不必要的手术干预并将相关风险降至最低。对于无症状病例,保守治疗通常有效,可确保患者获得良好预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/f6887c8e122c/cureus-0016-00000073523-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/9c997d1dad0f/cureus-0016-00000073523-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/3f2d8ba59d0a/cureus-0016-00000073523-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/7faffae2989d/cureus-0016-00000073523-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/f6887c8e122c/cureus-0016-00000073523-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/9c997d1dad0f/cureus-0016-00000073523-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/3f2d8ba59d0a/cureus-0016-00000073523-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/7faffae2989d/cureus-0016-00000073523-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/26a7/11636397/f6887c8e122c/cureus-0016-00000073523-i04.jpg

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Medicine (Baltimore). 2024 Feb 9;103(6):e37137. doi: 10.1097/MD.0000000000037137.
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Challenging Diagnosis of Lytic Bone Lesions Between Multiple Myeloma and Bone Metastasis of Primary Breast Cancer.多发性骨髓瘤与原发性乳腺癌骨转移中溶骨性骨病变的诊断挑战
Cureus. 2023 Nov 16;15(11):e48880. doi: 10.7759/cureus.48880. eCollection 2023 Nov.
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Removal of an intraosseous hemangioma of the frontal bone through an anterior hairline incision: a case report.
经前额发际线切口切除额骨骨内血管瘤:一例报告
Arch Craniofac Surg. 2023 Aug;24(4):189-192. doi: 10.7181/acfs.2023.00150. Epub 2023 Aug 20.
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Imaging features of intraosseous hemangiomas: beyond the mobile spine and calvarium.骨内血管瘤的影像学特征:超越活动脊柱和颅骨。
Skeletal Radiol. 2023 Sep;52(9):1739-1746. doi: 10.1007/s00256-023-04339-y. Epub 2023 Apr 13.
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Intraosseous Hemangioma with unusual presentation.表现异常的骨内血管瘤。
J Family Med Prim Care. 2022 Sep;11(9):5662-5666. doi: 10.4103/jfmpc.jfmpc_1673_21. Epub 2022 Oct 14.
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Am J Case Rep. 2022 Jun 23;23:e936984. doi: 10.12659/AJCR.936984.
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