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妊娠早期高危阶段的激素分析与超声检查(作者译)

[Hormone analyses and ultrasound examinations in high-risk early weeks of pregnancy (author's transl)].

作者信息

Gerhard I, Runnebaum B, Kubli F

出版信息

Z Geburtshilfe Perinatol. 1979 Oct;183(5):323-34.

PMID:396727
Abstract

The serum concentrations of HCG, HPL, progesterone and oestriol and ultrasonic findings were compared with one another in 42 women with normal pregnancy course, 51 women with haemorrhages and abortion and 27 women with haemorrhages and delivery on time. Correct diagnosis was most frequently possible with the help of ultrasound examination. However, it was possible to improve the accuracy of the diagnosis before the twelfth week of pregnancy by means of hormone analysis. If the hormone concentrations were normal, whereas ultrasound findings were either negative or not clear, intact pregnancy could be assumed. HCG and progesterone determination possessed the advantage of being reliably measurable even before cessation of menstrual bleeding. From the eighth to ninth weeks of pregnancy, determinations of HPL were also suitable for assessing endocrinal functions. After the twelfth week of pregnancy, the pregnancy conditions could be judged most safely by the ultrasound method.

摘要

对42例妊娠过程正常的妇女、51例有出血和流产情况的妇女以及27例有出血但按时分娩的妇女的血清人绒毛膜促性腺激素(HCG)、人胎盘催乳素(HPL)、孕酮和雌三醇浓度以及超声检查结果进行了相互比较。借助超声检查最常能做出正确诊断。然而,通过激素分析可以提高妊娠12周前诊断的准确性。如果激素浓度正常,而超声检查结果为阴性或不明确,则可假定妊娠正常。即使在月经出血停止之前,HCG和孕酮测定也具有可靠可测的优势。从妊娠第8至9周起,HPL测定也适用于评估内分泌功能。妊娠12周后,通过超声方法能最安全地判断妊娠情况。

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