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Flavonoids from the whole plants of and their anti-inflammatory activity.

作者信息

Li Ban-Ban, Sun Shao-Wei, Miao Shuang, Yang Li-Juan, Meng Xin-Yu, Gong Kai-Kai, Qi Shi-Zhou, Zhang Jin-Jie

机构信息

Department of Pharmacy, Binzhou Medical University Hospital, Binzhou, China.

Medical Research Center, Binzhou Medical University Hospital, Binzhou, China.

出版信息

Nat Prod Res. 2024 Dec 16:1-5. doi: 10.1080/14786419.2024.2440515.

DOI:10.1080/14786419.2024.2440515
PMID:39676596
Abstract

Medicinal plants in the high salinity and high alkaline environment might possess some special chemical constituents with new skeleton and high bioactivity. In this work, the main chemical constituents of namely flavonoids, were comprehensively studied for the first time. A new flavonoid together with five known compounds were isolated from the whole plants of Their structures were determined by the analysis of comprehensive spectroscopic data. All isolates were evaluated for their anti-inflammatory activity. Compound exhibited moderate anti-inflammatory activity on NO production with IC value of 20.5 ± 1.3 μM. In addition, 38 flavonoids were identified by UPLC-MS/MS method and 18 reported flavonoids were summarised.

摘要

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