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一项评估65岁及以上和65岁以下人群在农村重症监护病房中感染新冠病毒后的死亡率和发病率的回顾性观察研究。

A Retrospective Observational Study Evaluating COVID-19 Mortality and Morbidity in a Rural ICU Among People Over and Under 65.

作者信息

Ahmed Mohammed, Makhlof Mahmod, Kotgire Anand, Omar Mohammad, Ahmed Syed

机构信息

Medicine, University of East Anglia, Norwich, GBR.

Intensive Care Unit, Hatta Hospital, Dubai, ARE.

出版信息

Cureus. 2024 Nov 13;16(11):e73578. doi: 10.7759/cureus.73578. eCollection 2024 Nov.

Abstract

Background The literature surrounding COVID-19 mortality in the elderly compellingly leans towards the elderly faring worse. The populations of such literature often combined the rural and urban populations or simply discounted the rural population altogether. Anecdotal evidence suggests that this stigma is misplaced and that the elderly are not always at risk of the worst health outcomes. Method SARS-CoV-2-positive patients who were admitted to the ICU of Hatta Hospital were included in the study. They were split into two groups, those under and those over the age of 65. Percentage mortality, morbidity using Acute Physiology and Chronic Health Evaluation II (APACHE II), and duration of hospital admission were assessed in the two groups, and statistical analysis was performed. Results Seventy-two patients were deemed eligible for inclusion. Percentage mortality of the total population was 16.67% (N=12). In the under 65's arm the mortality percentage was 12.5% and the percentage mortality of the over 65's was 21.9% (N=7); chi-squared=1.13 (p=0.29). There was no statistical significance between mortality in the two arms. The global average time to discharge was 20.64 ± 1.98 days. The average time to discharge in the under-65's was 19.83± 2.64 days; the average time to discharge in the over-65 group was 21.66 ± 3.04 days; p= 0.65. The global average APACHE II score was 10.52 ± 0.77. The mean APACHE II score for the under 65's arm was 8.24 ± 0.95 while the mean APACHE II score for the over 65's was calculated at 13.2 ± 1.04: p=0.0008. Conclusion Overall, mortality was not significantly different, nor was their duration of stay. There was a significant difference in their morbidity; however, both groups had similar healthcare outcomes. The elderly did not face worse health outcomes than their younger counterparts. There is a gap in the literature discussing rural healthcare.

摘要

背景

围绕老年人感染新冠病毒死亡率的文献有力地表明,老年人的情况更糟。此类文献中的人群通常将农村和城市人口合并在一起,或者干脆完全忽略农村人口。轶事证据表明,这种偏见是错误的,老年人并不总是面临最糟糕的健康结果风险。

方法

纳入哈塔医院重症监护病房收治的新冠病毒检测呈阳性的患者。他们被分为两组,65岁以下和65岁以上。评估两组的死亡率、使用急性生理与慢性健康状况评分系统II(APACHE II)评估的发病率以及住院时间,并进行统计分析。

结果

72名患者被认为符合纳入标准。总人群的死亡率为16.67%(N = 12)。65岁以下组的死亡率为12.5%,65岁以上组的死亡率为21.9%(N = 7);卡方值 = 1.13(p = 0.29)。两组死亡率之间无统计学意义。全球平均出院时间为20.64 ± 1.98天。65岁以下组的平均出院时间为19.83 ± 2.64天;65岁以上组的平均出院时间为21.66 ± 3.04天;p = 0.65。全球平均APACHE II评分为10.52 ± 0.77。65岁以下组的平均APACHE II评分为8.24 ± 0.95,而65岁以上组的平均APACHE II评分为13.2 ± 1.04:p = 0.0008。

结论

总体而言,死亡率无显著差异,住院时间也无显著差异。发病率存在显著差异;然而,两组的医疗结果相似。老年人面临的健康结果并不比年轻人更糟。在讨论农村医疗保健的文献方面存在差距。

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