Wu Kuan-Hsien, Lee Jia-In, Lee Yung-Chin, Shen Jung-Tsung, Wang Hsun-Shuan, Tsao Yao-Hsuan, Wu Yi-Hsuan, Huang Shu-Pin, Chen Szu-Chia, Jhan Jhen-Hao, Geng Jiun-Hung
Department of Urology, Kaohsiung Municipal Siaogang Hospital, Kaohsiung City, Taiwan.
Department of Urology, Kaohsiung Medical University Hospital, Kaohsiung City, Taiwan.
PeerJ. 2024 Dec 11;12:e18639. doi: 10.7717/peerj.18639. eCollection 2024.
Menopause is associated with an increased risk of kidney stone disease (KSD). However, for postmenopausal women, how to avoid KSD has rarely been studied. The aim of this study was to explore whether drinking tea is associated with a reduction in the prevalence of KSD in postmenopausal women.
We collected 11,484 postmenopausal women from the Taiwan Biobank, and used questionnaires to obtain information on tea drinking, KSD, and comorbidities. The participants were divided into two groups according to habitual tea consumption: tea-drinking and non-tea-drinking groups. The association between habitual tea consumption and KSD was examined by logistic regression analysis.
There were 2,035 postmenopausal women in the tea-drinking group and 9,449 postmenopausal women in the non-tea-drinking group. The mean age of all participants was 61 years. Compared to the non-tea-drinking group, the tea-drinking group had a significantly lower prevalence of KSD (7% . 5%). The odds ratio (OR) of KSD was lower in those who habitually drank tea than in those who did not (OR = 0.78; 95% confidence interval [CI] [0.63 to 0.96]) after adjusting for confounders. Moreover, postmenopausal women with a daily intake of two cups of tea or more had a 30% reduced risk of KSD compared to those who did not habitually drink tea (OR = 0.71, 95% CI [0.56 to 0.90]).
Our results suggest that habitual tea drinking may be associated with a reduction in the prevalence of KSD in postmenopausal women. Further studies are warranted to investigate the protective effect of tea on the development of KSD.
绝经与肾结石疾病（KSD）风险增加相关。然而，对于绝经后女性，如何避免患KSD鲜有研究。本研究的目的是探讨饮茶是否与绝经后女性KSD患病率降低有关。
我们从台湾生物银行收集了11484名绝经后女性，并通过问卷获取饮茶、KSD及合并症的信息。参与者根据习惯性饮茶情况分为两组：饮茶组和不饮茶组。通过逻辑回归分析检验习惯性饮茶与KSD之间的关联。
饮茶组有2035名绝经后女性，不饮茶组有9449名绝经后女性。所有参与者的平均年龄为61岁。与不饮茶组相比，饮茶组的KSD患病率显著更低（7%对5%）。在调整混杂因素后，习惯性饮茶者患KSD的比值比（OR）低于不饮茶者（OR = 0.78；95%置信区间[CI][0.63至0.96]）。此外，与不习惯饮茶的绝经后女性相比，每日饮茶两杯或更多的绝经后女性患KSD的风险降低30%（OR = 0.71，95% CI[0.56至0.90]）。
我们的结果表明，习惯性饮茶可能与绝经后女性KSD患病率降低有关。有必要进一步研究茶对KSD发生的保护作用。
