Rawlings J M, Lucas M L
Gut. 1985 Feb;26(2):203-7. doi: 10.1136/gut.26.2.203.
Plastic electrodes have been developed for measuring pH in the human gastrointestinal tract. The electrodes have a plastic hydrogen ion sensitive membrane sealed to a length of fluid filled PVC tubing. Two recently developed hydrogen ion sensitive ligands have been examined. Their operational characteristics have been described. These electrodes have an electrical response of 52 to 58 mV/pH unit change in the range pH 4-9, with a diminished response outwith this range. They have a low resistance value and a fast response time of one second to reach 90% of their maximum response. The electrodes can be passed down the biopsy channel of an endoscope to obtain mucosal pH readings under direct vision. Readings obtained in this way using plastic electrodes are comparable to those obtained with glass electrodes. Alternatively, these electrodes can be joined to a Crosby capsule, allowing continuous recording of mucosal pH through to the jejunum during jejunal biopsy procedures. These electrodes can be used repeatedly or may be acceptable as inexpensive disposable items for sterile clinical use.
已开发出用于测量人体胃肠道pH值的塑料电极。这些电极有一个密封在一段充满液体的PVC管上的塑料氢离子敏感膜。研究了两种最近开发的氢离子敏感配体，并描述了它们的操作特性。这些电极在pH值4 - 9范围内，每单位pH值变化的电响应为52至58 mV，在此范围之外响应减弱。它们具有低电阻值和1秒的快速响应时间，可达到其最大响应的90%。电极可通过内窥镜的活检通道，在直视下获得黏膜pH值读数。使用塑料电极以这种方式获得的读数与使用玻璃电极获得的读数相当。或者，这些电极可连接到克罗斯比胶囊上，以便在空肠活检过程中持续记录直至空肠的黏膜pH值。这些电极可重复使用，也可作为廉价的一次性物品用于无菌临床，是可以接受的。
