Msarweh Amar, Shehadeh Mohammad Hakam, Abualrub Ahmad M, Malhes Waleed M, Msarweh Nadeen, Sinokrot Jenan Khaled, Aliwisat Ahmed H
Faculty of Medicine, Al-Quds University, Jerusalem, Palestine.
Department of Pediatric Surgery, Al-Makassed Islamic Charitable Hospital, Jerusalem, Palestine.
Front Pediatr. 2024 Nov 29;12:1460251. doi: 10.3389/fped.2024.1460251. eCollection 2024.
Teratomas are germ cell tumors that arise from the derivatives of the three germ cell layers. They are categorized into subtypes by the extent of maturation, with mature teratomas being the most common subtype. While they can arise in various extragonadal regions, including the retroperitoneum, their occurrence in the retroperitoneal space is extremely rare. It is even more exceptional for these tumors to be located within the adrenal gland. In this report, we describe an 18-day-old female infant who presented with a left suprarenal mass. The mass was detected during prenatal screening via ultrasound at 30 weeks of pregnancy. Evaluation after birth, including a chest and abdomen computed tomography (CT) scan, revealed a large, well-defined left suprarenal mass. The mass was surgically resected and found to measure 9 cm × 7 cm × 5 cm. Histopathological examination confirmed a cystic mature teratoma containing a variety of well-differentiated tissues. The patient has shown excellent progress over the 1-year follow-up, with no evidence of recurrence. Only a few cases of mature adrenal teratoma have been reported, highlighting the importance of this case report.
畸胎瘤是起源于三个胚层衍生物的生殖细胞肿瘤。它们根据成熟程度分为不同亚型,成熟畸胎瘤是最常见的亚型。虽然它们可发生于包括腹膜后在内的各种性腺外区域,但在腹膜后间隙发生极为罕见。这些肿瘤位于肾上腺内更为罕见。在本报告中,我们描述了一名18日龄的女婴,她出现左肾上腺肿块。该肿块在妊娠30周时通过超声产前筛查发现。出生后进行的评估,包括胸部和腹部计算机断层扫描(CT),显示左肾上腺有一个大的、边界清晰的肿块。该肿块经手术切除,大小为9 cm×7 cm×5 cm。组织病理学检查证实为囊性成熟畸胎瘤,含有多种分化良好的组织。患者在1年的随访中进展良好,无复发迹象。仅报道了少数成熟肾上腺畸胎瘤病例,凸显了本病例报告的重要性。