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全氟碳液体短期填塞治疗巨大视网膜裂孔相关视网膜脱离

Short-Term Endotamponade With Perfluorocarbon Liquids for Giant Retinal Tear-Associated Retinal Detachment.

作者信息

Kannan Naresh Babu, Vallinayagam MuthuKrishnan, Balakrishnan Tanya, Dey Sarkar Avik, Rajan Renu P, Ramasamy Kim

机构信息

Department of Vitreoretinal Services, Aravind Eye Hospital, Madurai (Tamil Nadu), India.

出版信息

J Vitreoretin Dis. 2024 Dec 13:24741264241305105. doi: 10.1177/24741264241305105.

Abstract

To investigate the use of short-term postoperative endotamponade with perfluorocarbon liquids (PFCLs) for the treatment of giant retinal tear-associated rhegmatogenous retinal detachment (RRD). This retrospective study evaluated patients who had 2-stage surgery, which entailed pars plana vitrectomy (PPV) completed in 2 consecutive surgeries spaced 5 days apart, during which a short-term tamponade with PFCL was used (Group 1), and patients who had conventional single-stage PPV with long-term silicone oil (SO) tamponade (Group 2). The study comprised 74 eyes of 68 patients, 52 in Group 1 and 22 in Group 2. The mean (±SD) patient age at presentation was 48.19 ± 15.73 years. Of the cases, 18.9% had high myopia and 13.5% had previous trauma. The improvement in best-corrected visual acuity (BCVA) was significantly better in Group 1 than in Group 2 at all postoperative visits ( = .004, postoperative day [POD] 15;  .002, POD 90;  .00006, final follow-up). Anatomic success (an attached retina) was achieved in 82.7% of patients in Group 1 and in 72.7% of patients in Group 2 ( .33). At the 6-month postoperative follow-up, 54.5% of patients and 50% of patients, respectively, had a logMAR BCVA of 1.00 or better ( .721). The mean change in intraocular pressure from baseline was statistically significant in both groups (Group 1,  .012; Group 2,  .018). Anatomic and functional outcomes in giant retinal tear-associated RRD can be improved with short-term postoperative endotamponade with PFCLs.

摘要

探讨术后短期使用全氟碳液体(PFCL)眼内填充治疗巨大裂孔性视网膜脱离(RRD)的效果。本回顾性研究评估了两组患者,第一组患者接受两阶段手术,即间隔5天连续进行两次经平坦部玻璃体切除术(PPV),术中使用PFCL进行短期眼内填充;第二组患者接受传统的单阶段PPV并长期使用硅油(SO)眼内填充。该研究共纳入68例患者的74只眼,其中第一组52例,第二组22例。患者就诊时的平均(±标准差)年龄为48.19±15.73岁。所有病例中,18.9%为高度近视,13.5%有既往外伤史。在所有术后随访中,第一组的最佳矫正视力(BCVA)改善情况均显著优于第二组(术后第15天,P = 0.004;术后第90天,P = 0.002;末次随访,P = 0.00006)。第一组82.7%的患者实现了解剖复位(视网膜附着),第二组为72.7%(P = 0.33)。术后6个月随访时,第一组和第二组分别有54.5%和50%的患者logMAR BCVA为1.00或更好(P = 0.721)。两组患者眼内压较基线的平均变化均有统计学意义(第一组,P = 0.012;第二组,P = 0.018)。术后短期使用PFCL眼内填充可改善巨大裂孔性视网膜脱离相关RRD的解剖和功能预后。

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