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基于碳量子点有机框架纳米材料的抗菌剂具有高抑制活性。

High Inhibition Activity of CQDs Organic Framework Nanomaterial-Based Antibacterials.

作者信息

Saparuddin Saparuddin, Tojang Djunarlin, Alimuddin Alimuddin, Arham Zul

机构信息

Biology Education Study Program, Faculty of Teacher Training and Education, Universitas, Sembilanbelas November Kolaka, Kabupaten Kolaka, Southeast Sulawesi 93517 Indonesia.

Agrotechnology Study Program, Faculty of Agriculture, Fisheries and Animal Husbandry, Universitas Sembilanbelas November Kolaka, Kabupaten Kolaka, Southeast Sulawesi 93517 Indonesia.

出版信息

Indian J Microbiol. 2024 Dec;64(4):1738-1746. doi: 10.1007/s12088-024-01230-9. Epub 2024 Mar 9.

DOI:10.1007/s12088-024-01230-9
PMID:39678982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11645363/
Abstract

Antibacterial agent based on modification of () extract into CQDs@ has been successfully synthesized and applied against and . plants were obtained from Buton Island, Southeast Sulawesi-Indonesia, and used as precursors for Carbon Quantum Dots (CQDs). In the synthesis, the dried leaves of were macerated, and then the filtrate was modified hydrothermally in a Teflon-lined stainless steel autoclave. The modification results produce nano-sized CQDs@ particles. The PSA test confirmed this, which described the CQDs@ particle size as 57.0 nm. The results of UV-Vis spectroscopy tests illustrate that the CQDs@ molecules experience π → π* and n → π* electronic transitions at a wavelength of 367 nm. Meanwhile, in the FTIR spectroscopy test, stretching vibrations from the functional groups -OH, C-H, C=O, C-O, and the benzene ring were observed at wave numbers 3415.93 cm, 2976.16 cm, 1641.42 cm, 1274.95 cm, and 692.44 cm, respectively. Based on the antibacterial activity test, it is known that CQDs@ has high inhibitory activity against and . The resulting inhibition diameters are 15.82 mm and 11.24 mm, respectively. This high inhibitory diameter further illustrates the potential of CQDs@ for its further application as an antibacterial material in the future.

摘要

基于将()提取物修饰为CQDs@的抗菌剂已成功合成,并用于对抗和。植物取自印度尼西亚东南苏拉威西省布顿岛,用作碳量子点(CQDs)的前体。在合成过程中,将的干燥叶片进行浸渍,然后将滤液在衬有聚四氟乙烯的不锈钢高压釜中进行水热修饰。修饰结果产生了纳米尺寸的CQDs@颗粒。PSA测试证实了这一点,其将CQDs@颗粒尺寸描述为57.0nm。紫外可见光谱测试结果表明,CQDs@分子在367nm波长处经历π→π和n→π电子跃迁。同时,在傅里叶变换红外光谱测试中,分别在波数3415.93cm、2976.16cm、1641.42cm、1274.95cm和692.44cm处观察到了-OH、C-H、C=O、C-O和苯环等官能团的伸缩振动。基于抗菌活性测试,已知CQDs@对和具有高抑制活性。所得抑制直径分别为15.82mm和11.24mm。这种高抑制直径进一步说明了CQDs@在未来作为抗菌材料进一步应用的潜力。

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