Suppr超能文献

青少年致心律失常性心脏骤停体外心肺复苏后的生存情况:ECPella(Impella体外膜肺氧合)——病例报告

Survival after extracorporeal cardiopulmonary resuscitation for adolescent arrhythmogenic arrest: ECPella (extracorporeal membrane oxygenation with Impella)-a case report.

作者信息

Lerner Anouska, Desai Ajay, Trimlett Richard, Till Janice, Chan-Dominy Amy

机构信息

Department of Paediatric Cardiology, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

PICU, Level 4, Royal Brompton Hospital, Sydney Street, London SW3 6NP, UK.

出版信息

Eur Heart J Case Rep. 2024 Nov 7;8(12):ytae581. doi: 10.1093/ehjcr/ytae581. eCollection 2024 Dec.

Abstract

BACKGROUND

The combined therapy with venoarterial extracorporeal membrane oxygenation and Impella (ECPella) has been shown to improve survival in acute cardiogenic shock (CS) in adult patient. Only three paediatric cases have been reported in a multicentre study.

CASE SUMMARY

We present our case, the first described to our knowledge in the UK, of a 15-year-old adolescent of Afro-Caribbean descent, weight 75 kg, who received extracorporeal cardiopulmonary resuscitation (E-CPR) and ECPella implantation. The patient suffered a sudden cardiac arrest at home; his mother called for an ambulance that arrived within 10 min and commenced life support with a LUCAS device. He received three doses of adrenaline and three desynchronized shocks for an underlying rhythm of ventricular fibrillation (VF) after which return of spontaneous circulation was achieved. He was then transferred to his local hospital where he had another VF arrest with successful cardioversion and was then transferred to our institution where on arrival he had another VF arrest and received E-CPR and ECPella implantation under the institutional adult shock programme within 3 h of in-hospital cardiac arrest. Following weaning from ECPella, the patient underwent cardiac and brain magnetic resonance imaging and serial echocardiograms with complete recovery of ventricular function. After implantation of cardiac defibrillator, he was discharged home without neurological sequelae. He remains asymptomatic from a cardiac perspective, with a normal cardiac examination and with no neurological sequelae at 2-year follow-up.

DISCUSSION

This is the first case description of ECPella use in a child in the UK and highlighted the importance of timely institution of E-CPR on survival benefit in fatal CS. The outcome success of post-resuscitation ECPella strategy in this adolescent was through collaborative interprofessional engagement of multiple supra-specialists within acute cardiology and critical care across paediatric and adult services and alignment with the institutional adult shock programme.

摘要

背景

静脉 - 动脉体外膜肺氧合与Impella联合治疗(ECPella)已被证明可提高成年急性心源性休克(CS)患者的生存率。在一项多中心研究中仅报告了3例儿科病例。

病例摘要

我们介绍了我们所知的英国首例病例,一名15岁的非裔加勒比裔青少年,体重75千克,接受了体外心肺复苏(E - CPR)和ECPella植入。患者在家中突发心脏骤停;他的母亲呼叫了救护车,救护车在10分钟内到达并使用LUCAS设备开始生命支持。他接受了三剂肾上腺素和三次非同步电击以治疗潜在的室颤(VF)节律,之后实现了自主循环恢复。然后他被转至当地医院,在那里他再次发生室颤骤停并成功复律,随后被转至我们的机构,到达时他再次发生室颤骤停,并在院内心脏骤停3小时内根据机构成人休克方案接受了E - CPR和ECPella植入。在撤离ECPella后,患者接受了心脏和脑部磁共振成像以及系列超声心动图检查,心室功能完全恢复。植入心脏除颤器后,他出院回家,没有神经后遗症。从心脏角度来看,他仍然无症状,心脏检查正常,在2年随访时没有神经后遗症。

讨论

这是英国首例关于儿童使用ECPella的病例描述,并强调了及时实施E - CPR对致命性CS生存获益的重要性。该青少年复苏后ECPella策略的成功结果是通过儿科和成人服务中急性心脏病学和重症监护领域的多个超专科医生之间的跨专业协作参与,并与机构成人休克方案保持一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a61b/11643901/edc5d9e6547f/ytae581il1.jpg

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验