Li Yue, Xu Huiqiong, Zhang Ting, Lu Xianying, Xie Xuemei, Gao Jing
College of Nursing, Chengdu University of Traditional Chinese Medicine, Chengdu, PR China.
Division of Abdominal Tumor Multimodality Treatment, Cancer Center, West China Hospital, Sichuan University/West China School of Nursing, Sichuan University.
J Stroke Cerebrovasc Dis. 2025 Feb;34(2):108201. doi: 10.1016/j.jstrokecerebrovasdis.2024.108201. Epub 2024 Dec 15.
Systematic evaluation of factors influencing social isolation in stroke patients for further intervention studies.
We searched for observational studies in 7 databases from inception to January 2024. Two researchers performed literature screening, quality assessment, and data extraction independently according to inclusion and exclusion criteria, and meta-analysis was performed using R4.3.1 software.
A total of 10 studies with a total sample size of 4162 cases were included. Meta-analysis showed that social isolation in stroke patients was associated with economic status (β'=-0.21, 95%CI:0.39, -0.02; P=0.0261), degree of education (β'=-0.16, 95%CI:0.29, -0.03; P=0.0171), marital status (β'=0.13, 95%CI:0.04, 0.23; P=0.0069), social support (β'=-0.37, 95%CI;-0.50, -0.25; P<0.0001), stigma(β'=0.48, 95%CI:0.25, 0.72; P<0.0001), symptom burden (β'=0.25, 95%CI:0.18, 0.31; P<0.0001), course of disease (β'=0.23, 95%CI:0.08, 0.37; P=0.0021), combined chronic diseases (β'=0.14, 95%CI:0.04, 0.24; P=0.0057), and limb function (β'=0.33, 95%CI:0.23, 0.43; P<0.0001) were associated. Meta-regression and subgroup analyses showed that disease stage and sample source were sources of heterogeneity.
There are many factors influencing the social isolation of stroke patients, and healthcare professionals should take timely and targeted measures to prevent and intervene effectively, with a view to improving the social participation of stroke patients and reducing their social isolation.
系统评估影响脑卒中患者社会隔离的因素，以供进一步的干预研究。
我们检索了7个数据库从建库至2024年1月的观察性研究。两名研究人员根据纳入和排除标准独立进行文献筛选、质量评估和数据提取，并使用R4.3.1软件进行荟萃分析。
共纳入10项研究，总样本量为4162例。荟萃分析表明，脑卒中患者的社会隔离与经济状况（β'=-0.21，95%CI：0.39，-0.02；P=0.0261）、教育程度（β'=-0.16，95%CI：0.29，-0.03；P=0.0171）、婚姻状况（β'=0.13，95%CI：0.04，0.23；P=0.0069）、社会支持（β'=-0.37，95%CI：-0.50，-0.25；P<0.0001）、耻辱感（β'=0.48，95%CI：0.25，0.72；P<0.0001）、症状负担（β'=0.25，95%CI：0.18，0.31；P<0.0001）、病程（β'=0.23，95%CI：0.08，0.37；P=0.0021）、合并慢性病（β'=0.14，95%CI：0.04，0.24；P=0.0057）以及肢体功能（β'=0.33，95%CI：0.23，0.43；P<0.0001）相关。荟萃回归和亚组分析表明，疾病阶段和样本来源是异质性的来源。
影响脑卒中患者社会隔离的因素众多，医护人员应及时采取有针对性的措施进行有效预防和干预，以期提高脑卒中患者的社会参与度，减少其社会隔离。
