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一只复发性喉腺癌猫接受多模式治疗后的长期结果。

Long-term outcome following multimodality treatment in a cat with recurrent laryngeal adenocarcinoma.

作者信息

Sesanto Christine, Lawrence Jessica, Holkham Jocelyn, Serra Juan Carlos, Bavcar Spela, Parys Magdalena

机构信息

Cancer Care Centre, Willows Veterinary Centre & Referral Service, Solihull, UK.

Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, California, USA.

出版信息

Vet Radiol Ultrasound. 2025 Jan;66(1):e13466. doi: 10.1111/vru.13466.

Abstract

A 9.5-year-old male neutered domestic short-haired cat received two courses of postoperative, definitive-intent conformal radiation therapy (RT) for recurrent laryngeal adenocarcinoma (LACA). Adjuvant RT was prescribed (16 × 3.0 Gy, total 48 Gy) following incomplete resection. Following tumor recurrence and subsequent incomplete resection 31.5 months after the first course, a second course was prescribed (20 × 2.5 Gy, total 50 Gy). Acute and late adverse events were mild. No evidence of local recurrence was documented 42 months following the second course when the cat was euthanized for renal disease. This first report of long-term control in a cat with LACA supports further evaluation of surgery and definitive-intent RT.

摘要

一只9.5岁已绝育的雄性家养短毛猫因复发性喉腺癌(LACA)接受了两个疗程的术后根治性适形放射治疗(RT)。在不完全切除后给予辅助放疗(16×3.0Gy,总计48Gy)。在第一个疗程31.5个月后肿瘤复发并随后不完全切除,之后给予第二个疗程(20×2.5Gy,总计50Gy)。急性和晚期不良事件均较轻。第二个疗程42个月后,这只猫因肾病实施安乐死时,未记录到局部复发的证据。这篇关于猫LACA长期控制的首例报告支持对手术和根治性放疗进行进一步评估。

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