Cascajosa-Lira Antonio, Pichardo Silvia, Baños Alberto, Aguinaga-Casañas María Arántzazu, Ricci Andrea, Frabetti Andrea, Barausse Andrea, Jos Angeles, Cameán Ana M
Área de Toxicología, Facultad de Farmacia, Universidad de Sevilla, 41012 Seville, Spain.
DMC Research Center, Camino de Jayena, 82, 18620 Alhendín, Spain.
Foods. 2024 Dec 9;13(23):3976. doi: 10.3390/foods13233976.
The rabbit farming industry is growing due to the rising demand for healthy, sustainable meat. Rabbit meat's nutritional benefits and low environmental impact appeal to health-conscious consumers. To enhance economic sustainability, efforts focus on reducing disease susceptibility and antibiotic use through improved biosecurity and natural additives, such as organosulphur compounds from plants, which have shown promise in studies for boosting productivity and health. This study aimed to investigate the effects of PTSO supplementation on farm rabbits. Over and after a 76-day period, various parameters were assessed to measure the impacts on rabbit growth, health, biochemical parameters, muscle metabolism, and intestinal microbiota. The rabbit groups received either a control diet or a diet supplemented with extract. The results showed significant improvements in growth performance for rabbits fed with extract, including higher final weights, increased average daily gain (ADG), and lower mortality rates. A biochemical analysis revealed normal values for the parameters measured in the treated group. A muscle analysis evidenced the presence of a few metabolites of PTSO. A gut microbiota analysis indicated distinct differences between the control and treated groups, increasing the presence of some strains that can influence positively the growth of rabbits. This study highlights the potential benefits of PTSO supplementation for improving growth performance, health parameters, and gut microbiota composition in farm rabbits, suggesting its efficacy as a dietary additive.
由于对健康、可持续肉类的需求不断增加，养兔业正在发展。兔肉的营养价值和对环境的低影响吸引了注重健康的消费者。为了提高经济可持续性，人们致力于通过改善生物安全措施和使用天然添加剂（如植物中的有机硫化合物，研究表明其在提高生产力和健康方面有前景）来降低疾病易感性和抗生素使用。本研究旨在调查补充PTSO对养殖兔的影响。在76天期间及之后，评估了各种参数，以衡量对兔子生长、健康、生化参数、肌肉代谢和肠道微生物群的影响。兔组分别接受对照饮食或补充提取物的饮食。结果显示，喂食提取物的兔子生长性能有显著改善，包括最终体重更高、平均日增重（ADG）增加和死亡率降低。生化分析显示治疗组测量参数的值正常。肌肉分析证明存在一些PTSO的代谢物。肠道微生物群分析表明对照组和治疗组之间存在明显差异，增加了一些可对兔子生长产生积极影响的菌株的存在。本研究强调了补充PTSO对改善养殖兔生长性能、健康参数和肠道微生物群组成的潜在益处，表明其作为饲料添加剂的有效性。
