Deleanu Iuliana Mihaela, Busuioc Cristina, Deleanu Mariana, Stoica-Guzun Anicuţa, Rotaru Mădălina, Ștefan Vasile Alexandru, Isopencu Gabriela
Faculty of Chemical Engineering and Biotechnology, National University of Science and Technology "Politehnica" Bucharest, 1-7 Polizu Street, 011061 Bucharest, Romania.
Institute of Cellular Biology and Pathology "Nicolae Simionescu", Romanian Academy, 8 Hasdeu Street, 050568 Bucharest, Romania.
Int J Mol Sci. 2024 Nov 30;25(23):12890. doi: 10.3390/ijms252312890.
Bacterial cellulose (BC) has earned a well-defined place among biopolymers due to its unique physicochemical properties. Unfortunately, native BC lacks antimicrobial and antioxidant properties. To address this limitation, many BC-based nanocomposites with antimicrobial properties have been developed, primarily for applications in the biomedical field, but also for use in food packaging. Many nanoparticles can be incorporated into BC membranes, often in combination with other bioactive molecules. Among the available methods for nanoparticle synthesis, green synthesis has emerged as promising, as it avoids the use of hazardous chemicals. The aim of this paper is to develop and characterize antimicrobial composite materials fabricated using carboxymethyl cellulose (CMC) and bacterial cellulose fibrils loaded with zinc oxide and silver nanoparticles (NPs) obtained using turmeric extract by green synthesis. NP-loaded CMC-BC composites were characterized using scanning electron microscopy (SEM) coupled with energy dispersive X-ray spectroscopy (EDX), attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy, Grazing incidence X-ray diffraction (GI-XRD), and thermal analysis (TA). The antibacterial potential of such composites was tested against , , and .
细菌纤维素(BC)因其独特的物理化学性质在生物聚合物中占据了明确的地位。不幸的是,天然BC缺乏抗菌和抗氧化性能。为了解决这一局限性,人们已经开发了许多具有抗菌性能的基于BC的纳米复合材料,主要用于生物医学领域,也用于食品包装。许多纳米颗粒可以被掺入BC膜中,通常还会与其他生物活性分子结合使用。在现有的纳米颗粒合成方法中,绿色合成已成为一种很有前景的方法,因为它避免了使用有害化学物质。本文的目的是开发并表征使用羧甲基纤维素(CMC)和细菌纤维素原纤维制备的抗菌复合材料,这些原纤维负载了通过绿色合成法利用姜黄提取物获得的氧化锌和银纳米颗粒(NPs)。使用扫描电子显微镜(SEM)结合能量色散X射线光谱(EDX)、衰减全反射傅里叶变换红外(ATR-FTIR)光谱、掠入射X射线衍射(GI-XRD)和热分析(TA)对负载NP的CMC-BC复合材料进行了表征。测试了此类复合材料对 、 和 的抗菌潜力。