Maskowicz Dominik, Maroszek Kacper, Jendrzejewski Rafał, Sawczak Mirosław
Photophysics Department, The Szewalski Institute of Fluid-Flow Machinery, Polish Academy of Sciences, Fiszera 14, 80-231 Gdańsk, Poland.
Materials (Basel). 2024 Nov 25;17(23):5778. doi: 10.3390/ma17235778.
Hydroxyapatite (HAp) is one of the most widely studied materials for utilization in the development of artificial implants. Research is mainly aimed at the production and modification of HAp coatings for simplification of the deposition process, cost reduction, and increase in biocompatibility. In this paper, the authors deposited HAp synthetic microparticles by means of matrix-assisted pulsed laser evaporation (MAPLE) on Ti6Al4V alloy plate substrates and obtained uniform HAp coatings without further treatment or modifications. The authors utilized a tunable pulsed laser to adjust its wavelength to the selected solvents, in order to optimize the process for deposition speed and quality. The following solvents were used as matrices: deionized water, isopropyl alcohol, and a 3:2 mixture of isopropanol:acetonitrile. Obtained coatings were examined by means of scanning electron microscopy, Raman spectroscopy, X-ray diffraction, and profilometry in order to evaluate coating quality, uniformity, and structural integrity. MAPLE deposition allowed the acquisition of approx. 200 nm thick coatings for water and isopropanol matrices and approx. 320 nm for isopropanol:acetonitrile matrix, which indicates an increase in deposition rate by 37%. The obtained coatings meet requirements for further biocompatibility testing, material modification, and composite synthesis.
羟基磷灰石（HAp）是人工植入体开发中研究最为广泛的材料之一。研究主要致力于HAp涂层的制备与改性，以简化沉积工艺、降低成本并提高生物相容性。在本文中，作者通过基质辅助脉冲激光蒸发（MAPLE）法在Ti6Al4V合金板基底上沉积了HAp合成微粒，且无需进一步处理或改性即可获得均匀的HAp涂层。作者使用可调谐脉冲激光将其波长调整至选定的溶剂，以优化沉积速度和质量的工艺。使用了以下溶剂作为基质：去离子水、异丙醇以及异丙醇与乙腈体积比为3:2的混合物。通过扫描电子显微镜、拉曼光谱、X射线衍射和轮廓仪对所得涂层进行检测，以评估涂层质量、均匀性和结构完整性。MAPLE沉积法可获得水和异丙醇基质的约200 nm厚涂层，异丙醇与乙腈基质的约320 nm厚涂层，这表明沉积速率提高了37%。所得涂层满足进一步生物相容性测试、材料改性和复合材料合成的要求。
