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在罗马尼亚一家三级中心使用IBD Disk对炎症性肠病患者残疾情况的横断面评估

A Cross-Sectional Evaluation of Disability in Inflammatory Bowel Disease Using IBD Disk in a Tertiary Center from Romania.

作者信息

Muru Oana-Maria, Pop Corina Silvia, Filip Petruța Violeta, Tiucă Nicoleta, Diaconu Laura Sorina

机构信息

Department of Internal Medicine 2 and Gastroenterology, Bucharest University Emergency Hospital, 050098 Bucharest, Romania.

Carol Davila University of Medicine, 050474 Bucharest, Romania.

出版信息

J Clin Med. 2024 Nov 26;13(23):7168. doi: 10.3390/jcm13237168.

Abstract

: The management of inflammatory bowel disease (IBD) includes, besides the control of symptoms, the prevention of organ damage and the improvement of the overall disability. : A single-centered, cross-sectional, non-interventional and population-based study was conducted between October 2023 and August 2024 in the Department of Internal Medicine 2 and Gastroenterology of Bucharest Emergency University Hospital to assess the disease disability and quality of life impact using IBD-disk and correlation with different parameters. : We included 112 patients; their mean age was 52.35 ± 16.67 years, with a disease duration of 114.9 ± 97.93 months. The majority of patients were represented by men (51.79%). We observed a strong correlation between the CDAI score and overall disability compared to the Mayo score for UC ( = 0.0068). Also, patients with CD and stenotic patterns, as well as the presence of extraintestinal complications, have associated high disability scores. Low hemoglobin levels are associated with high disability ( = 0.0164), while biological treatment is associated with low disability ( = 0.0481). : IBD-disk can be used as a valuable tool to assess disability in patients with IBD, also in terms of the activity of the disease, but mostly in terms of the psychological burden of the disease.

摘要

炎症性肠病(IBD)的管理除了控制症状外,还包括预防器官损伤和改善整体残疾状况。2023年10月至2024年8月期间,在布加勒斯特急救大学医院内科2和胃肠病学系进行了一项单中心、横断面、非干预性和基于人群的研究,以使用IBD量表评估疾病残疾情况和生活质量影响,并与不同参数进行相关性分析。我们纳入了112例患者;他们的平均年龄为52.35±16.67岁,病程为114.9±97.93个月。大多数患者为男性(51.79%)。与UC的梅奥评分相比,我们观察到CDAI评分与整体残疾之间存在很强的相关性(P = 0.0068)。此外,患有CD和狭窄型的患者以及存在肠外并发症的患者,其残疾评分较高。低血红蛋白水平与高残疾相关(P = 0.0164),而生物治疗与低残疾相关(P = 0.0481)。IBD量表可作为评估IBD患者残疾情况的有价值工具,不仅可用于评估疾病活动度,而且主要可用于评估疾病的心理负担。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c5e/11642591/42bd669ef427/jcm-13-07168-g001.jpg

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