Muru Oana-Maria, Pop Corina Silvia, Filip Petruța Violeta, Tiucă Nicoleta, Diaconu Laura Sorina
Department of Internal Medicine 2 and Gastroenterology, Bucharest University Emergency Hospital, 050098 Bucharest, Romania.
Carol Davila University of Medicine, 050474 Bucharest, Romania.
J Clin Med. 2024 Nov 26;13(23):7168. doi: 10.3390/jcm13237168.
: The management of inflammatory bowel disease (IBD) includes, besides the control of symptoms, the prevention of organ damage and the improvement of the overall disability. : A single-centered, cross-sectional, non-interventional and population-based study was conducted between October 2023 and August 2024 in the Department of Internal Medicine 2 and Gastroenterology of Bucharest Emergency University Hospital to assess the disease disability and quality of life impact using IBD-disk and correlation with different parameters. : We included 112 patients; their mean age was 52.35 ± 16.67 years, with a disease duration of 114.9 ± 97.93 months. The majority of patients were represented by men (51.79%). We observed a strong correlation between the CDAI score and overall disability compared to the Mayo score for UC ( = 0.0068). Also, patients with CD and stenotic patterns, as well as the presence of extraintestinal complications, have associated high disability scores. Low hemoglobin levels are associated with high disability ( = 0.0164), while biological treatment is associated with low disability ( = 0.0481). : IBD-disk can be used as a valuable tool to assess disability in patients with IBD, also in terms of the activity of the disease, but mostly in terms of the psychological burden of the disease.
炎症性肠病(IBD)的管理除了控制症状外,还包括预防器官损伤和改善整体残疾状况。2023年10月至2024年8月期间,在布加勒斯特急救大学医院内科2和胃肠病学系进行了一项单中心、横断面、非干预性和基于人群的研究,以使用IBD量表评估疾病残疾情况和生活质量影响,并与不同参数进行相关性分析。我们纳入了112例患者;他们的平均年龄为52.35±16.67岁,病程为114.9±97.93个月。大多数患者为男性(51.79%)。与UC的梅奥评分相比,我们观察到CDAI评分与整体残疾之间存在很强的相关性(P = 0.0068)。此外,患有CD和狭窄型的患者以及存在肠外并发症的患者,其残疾评分较高。低血红蛋白水平与高残疾相关(P = 0.0164),而生物治疗与低残疾相关(P = 0.0481)。IBD量表可作为评估IBD患者残疾情况的有价值工具,不仅可用于评估疾病活动度,而且主要可用于评估疾病的心理负担。