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一种新型气溶胶喷射打印应变传感器在可变刚度动脉模拟器应用中的可行性评估的初步特性分析。

Preliminary Characterization of a Novel Aerosol Jet-Printed Strain Sensor for Feasibility Assessment in a Variable Stiffness Arterial Simulator Application.

作者信息

Filippi Federico, Fiori Giorgia, Genovesi Annalisa, Barletta Massimiliano, Lancini Matteo, Serpelloni Mauro, Scorza Andrea, Sciuto Salvatore Andrea

机构信息

Department of Industrial, Electronic and Mechanical Engineering, University of Roma Tre, 00146 Rome, Italy.

Department of Medical and Surgical Specialties, Radiological Sciences, and Public Health, University of Brescia, 25121 Brescia, Italy.

出版信息

Sensors (Basel). 2024 Dec 3;24(23):7725. doi: 10.3390/s24237725.

Abstract

Wearable strain sensors are widespread in many fields, including the biomedical field where they are used for their stretchability and ability to be applied to non-regular surfaces. The study of the propagation speed of the pressure wave generated by the heartbeat within vessels, i.e., the Pulse Wave Velocity (PWV), is of significant relevance in this field to assess arterial stiffness, a parameter commonly used for the early diagnosis of cardiovascular diseases. In this context, arterial simulators are useful tools to study the relationship between the PWV and other hemodynamic quantities in vitro. This study aims to characterize novel strain sensors to assess their suitability within an arterial simulator capable of varying the stiffness of an arterial surrogate by varying the transmural pressure. Six sensors deposited on arterial surrogates by Aerosol Jet Printing technology were subjected to deformation through a load frame. The results show that the sensors were able to distinguish strains of 0.1%, the maximum strain was around 6-8%, and the fatigue strength depended strongly on the strain rate.

摘要

可穿戴应变传感器在许多领域广泛应用,包括生物医学领域,在该领域中,它们因其可拉伸性以及能够应用于不规则表面的特性而被使用。研究心跳在血管内产生的压力波的传播速度,即脉搏波速度(PWV),在该领域对于评估动脉僵硬度具有重要意义,动脉僵硬度是常用于心血管疾病早期诊断的一个参数。在此背景下,动脉模拟器是在体外研究PWV与其他血流动力学量之间关系的有用工具。本研究旨在表征新型应变传感器,以评估它们在能够通过改变跨壁压力来改变动脉替代物僵硬度的动脉模拟器中的适用性。通过气溶胶喷射印刷技术沉积在动脉替代物上的六个传感器通过加载框架进行变形。结果表明,这些传感器能够分辨出0.1%的应变,最大应变约为6 - 8%,并且疲劳强度强烈依赖于应变率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63e4/11645093/ad19745e3a70/sensors-24-07725-g001.jpg

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