• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一名患有脾转移、脾脓肿和血小板减少症的结肠癌患者:病例报告。

A colon cancer patient with splenic metastasis associated with a splenic abscess and thrombocytopenia: A case report.

作者信息

Cui Fang, Zhu Rongfeng, Qian Zhangjun, Zhang Yunlei

机构信息

Department of Oncology, The Affiliated Yixing Hospital of Jiangsu University, Wuxi, Jiangsu Province, China.

Ultrasound Medical Imaging Department, The Affiliated Yixing Hospital of Jiangsu University, Wuxi, Jiangsu Province, China.

出版信息

Medicine (Baltimore). 2024 Dec 13;103(50):e40936. doi: 10.1097/MD.0000000000040936.

DOI:10.1097/MD.0000000000040936
PMID:39686448
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11651490/
Abstract

RATIONALE

Splenic metastases concomitant with abscesses are rare and challenging for clinicians. The primary treatment options include splenectomy and ultrasound-guided percutaneous perforation and drainage.

PATIENT CONCERNS

A case of splenic abscess in a colon cancer patient with splenic metastasis who developed chills and fever for approximately 2 weeks. However, the best broad-spectrum antibiotics are ineffective. Moreover, the patient had a high bleeding risk for percutaneous perforation due to a low platelet count.

DIAGNOSES

Colon cancer, splenic metastasis, splenic abscess, thrombocytopenia.

INTERVENTIONS

Ultrasound-guided percutaneous splenic abscess perforation and drainage were performed after platelet transfusion and stimulation of platelet production in the bone marrow.

OUTCOMES

His fever was immediately relieved at night and thrombocytopenia did not relapse thereafter. His platelet count increased rapidly and reached 121 × 109/L 3 days later.

LESSONS

Spleen metastasis in tumor patients necessitates vigilance for the potential development of spleen abscess. A less invasive procedure can be feasible in cases of low platelet count without significant coagulation dysfunction. When there is no alternative therapeutic schedule, doctors should fully evaluate the risks and benefits.

摘要

理论依据

脾脏转移瘤合并脓肿较为罕见,给临床医生带来挑战。主要治疗选择包括脾切除术以及超声引导下经皮穿刺引流。

患者情况

一名结肠癌伴脾脏转移的患者出现脾脏脓肿,寒战、发热约2周。然而,使用最佳的广谱抗生素治疗无效。此外,患者因血小板计数低,经皮穿刺存在高出血风险。

诊断

结肠癌、脾脏转移、脾脏脓肿、血小板减少症。

干预措施

在输注血小板并刺激骨髓生成血小板后,进行了超声引导下经皮脾脏脓肿穿刺引流。

结果

当晚其发热立即缓解,此后血小板减少症未复发。其血小板计数迅速上升,3天后达到121×10⁹/L。

经验教训

肿瘤患者出现脾脏转移时,必须警惕脾脏脓肿的潜在发生。对于血小板计数低且无明显凝血功能障碍的患者,采用侵入性较小的手术可能是可行的。当没有其他治疗方案时,医生应充分评估风险和益处。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/701598cc4292/medi-103-e40936-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/b1c7ab8cb757/medi-103-e40936-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/472422acd404/medi-103-e40936-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/701598cc4292/medi-103-e40936-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/b1c7ab8cb757/medi-103-e40936-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/472422acd404/medi-103-e40936-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/71b8/11651490/701598cc4292/medi-103-e40936-g003.jpg

相似文献

1
A colon cancer patient with splenic metastasis associated with a splenic abscess and thrombocytopenia: A case report.一名患有脾转移、脾脓肿和血小板减少症的结肠癌患者:病例报告。
Medicine (Baltimore). 2024 Dec 13;103(50):e40936. doi: 10.1097/MD.0000000000040936.
2
Synchronous isolated splenic metastasis from colon carcinoma and concomitant splenic abscess: a case report and review of the literature.结肠癌同步孤立性脾转移及并发脾脓肿:一例报告并文献复习
World J Gastroenterol. 2007 Nov 7;13(41):5516-20. doi: 10.3748/wjg.v13.i41.5516.
3
Splenic abscess owing to cancer at the splenic flexure: A case report and comprehensive review.脾曲癌导致的脾脓肿:一例报告及综合综述
Medicine (Baltimore). 2016 Sep;95(38):e4941. doi: 10.1097/MD.0000000000004941.
4
Splenic abscess associated with colon cancer: a case report.脾脓肿合并结肠癌:一例报告
Jpn J Clin Oncol. 1993 Dec;23(6):384-8.
5
The role of percutaneous US-guided drainage in the treatment of splenic abscess. Case report and review of the literature.经皮超声引导下引流在脾脓肿治疗中的作用。病例报告及文献综述。
Ann Ital Chir. 2012 Sep-Oct;83(5):433-6.
6
[A case report of a splenic abscess due to colon cancer in splenic flexure infiltrating into spleen].[一例因脾曲结肠癌浸润脾脏导致脾脓肿的病例报告]
Gan To Kagaku Ryoho. 2014 Nov;41(12):1657-9.
7
[Case Report of a Splenic Abscess Due to Colon Cancer].[一例因结肠癌导致脾脓肿的病例报告]
Gan To Kagaku Ryoho. 2015 Nov;42(12):2227-9.
8
Ultrasound-guided percutaneous catheter drainage of splenic abscess.超声引导下经皮脾脓肿导管引流术。
Pediatr Radiol. 2004 Mar;34(3):271-3. doi: 10.1007/s00247-003-1068-5. Epub 2003 Oct 7.
9
Multiple large splenic abscesses managed with computed tomography-guided percutaneous catheter drainage in children.儿童多发性巨大脾脓肿采用计算机断层扫描引导下经皮导管引流治疗。
Pediatr Neonatol. 2013 Dec;54(6):409-12. doi: 10.1016/j.pedneo.2013.01.008. Epub 2013 Mar 1.
10
Ultrasound-guided percutaneous drainage of pyogenic splenic abscesses.超声引导下经皮穿刺引流化脓性脾脓肿
J Clin Ultrasound. 1994 Mar-Apr;22(3):161-6. doi: 10.1002/jcu.1870220303.

本文引用的文献

1
Colonic Adenocarcinoma Presenting as Splenic Abscess Secondary to Suspected Microperforation.结肠腺癌表现为疑似微小穿孔继发脾脓肿。
J Investig Med High Impact Case Rep. 2020 Jan-Dec;8:2324709620978317. doi: 10.1177/2324709620978317.
2
Splenic Abscess: An Uncommon Entity with Potentially Life-Threatening Evolution.脾脓肿:一种罕见且可能危及生命的病症。
Can J Infect Dis Med Microbiol. 2018 Jan 31;2018:8610657. doi: 10.1155/2018/8610657. eCollection 2018.
3
Splenic abscess in cancer chemotherapy.癌症化疗中的脾脓肿
BMC Res Notes. 2015 Nov 11;8:665. doi: 10.1186/s13104-015-1655-1.
4
[A case report of a splenic abscess due to colon cancer in splenic flexure infiltrating into spleen].[一例因脾曲结肠癌浸润脾脏导致脾脓肿的病例报告]
Gan To Kagaku Ryoho. 2014 Nov;41(12):1657-9.
5
Splenic metastases--not a frequent problem, but an underestimate location of metastases: epidemiology and course.脾转移瘤——并非常见问题,但却是转移瘤的一个易被低估的部位:流行病学与病程
J Cancer Res Clin Oncol. 2009 May;135(5):667-71. doi: 10.1007/s00432-008-0502-3. Epub 2008 Oct 21.
6
Splenic metastases from mucinous neoplasms of the appendix and colon.阑尾和结肠黏液性肿瘤的脾转移
Tumori. 2006 Mar-Apr;92(2):104-12. doi: 10.1177/030089160609200204.
7
Clinical characteristics and prognostic factors of splenic abscess: a review of 67 cases in a single medical center of Taiwan.脾脓肿的临床特征及预后因素:台湾某单一医学中心67例病例回顾
World J Gastroenterol. 2006 Jan 21;12(3):460-4. doi: 10.3748/wjg.v12.i3.460.
8
Splenic metastases in a large unselected autopsy series.一个大型非选择性尸检系列中的脾转移瘤。
Pathol Res Pract. 2006;202(5):351-6. doi: 10.1016/j.prp.2005.12.008. Epub 2006 Feb 20.
9
[Pyogenic splenic abscesses. A review of 8 cases].
Rev Med Interne. 2005 Jul;26(7):541-4. doi: 10.1016/j.revmed.2005.03.008.
10
Management of splenic abscess in a critically ill patient.
Surg Laparosc Endosc Percutan Tech. 2004 Apr;14(2):49-52. doi: 10.1097/00129689-200404000-00001.