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铥光纤激光和钬激光碎石术引起的肾结石温度分布模拟

Simulation of the temperature distribution of kidney stones induced by thulium fiber laser and Ho: YAG laser lithotripsy.

作者信息

Singh Khwairakpam Shantakumar, Premabati Thangjam

机构信息

Department of Education, Assam University, Silchar, Assam, India.

Department of Biotechnology, Mizoram University, Aizawl, Mizoram, India.

出版信息

Lasers Med Sci. 2024 Dec 17;39(1):297. doi: 10.1007/s10103-024-04255-0.

Abstract

Simulation studies on temperature distribution in laser ablation help predict ablation rates, laser settings, and thermal damage. Despite the limited number of reported numerical studies on the temperature distribution of kidney fluid, there is no simulation study for kidney stone temperature distribution. We employ a numerical approach to study the kidney stone temperature distribution and predict ablation rates, which is an important parameter for clinical lithotripsy. The study looked at how the thulium fiber laser and the Ho:YAG laser differ in terms of temperature profile and ablation depth of kidney stones like calcium oxide monohydrate. The ablation depth increased from 152.7 µm to 489.7 µm when the TFL laser (operated at 10 Hz repetition rate and 1 ms pulse width) fluence increased from 764 J/cm to 1146 J/cm. Correspondingly, the depth increased from 21 µm to 68 µm for the Ho: YAG laser operated at 3 Hz and 0.22 ms pulse width. We attribute this to an increase in temperature with laser energy. We further investigated the effect of pulse width on ablation depth by considering three different TFL pulse widths: 0.5 ms, 0.75 ms, and 1 ms. There was a decrease in ablation depths from 402.5 µm to 242.6 µm when the pulse width increased from 0.5 ms to 1 ms. Because of lower water absorption coefficients, the Ho:YAG laser (70 mJ/10 Hz) produced a smaller ablation depth and temperature profile than the thulium fiber laser (70 mJ/10 Hz). Experimental results from the literature validated the simulation. We found that the Ho:YAG laser worked better for ablation when it was set to 0.2 J/100 Hz for the Ho:YAG laser and 0.4 J/50 Hz for the TFL laser, which were clinical laser settings that we found in the literature. This indicates that, in addition to laser absorption by water, the laser parameters also significantly influence temperature distribution and ablation.

摘要

激光消融温度分布的模拟研究有助于预测消融速率、激光设置和热损伤。尽管关于肾液温度分布的数值研究报告数量有限,但尚无关于肾结石温度分布的模拟研究。我们采用数值方法研究肾结石温度分布并预测消融速率,消融速率是临床碎石术的一个重要参数。该研究考察了掺铥光纤激光器和钬激光在温度分布和氧化钙一水合物等肾结石消融深度方面的差异。当掺铥光纤激光器(以10Hz重复频率和1ms脉冲宽度运行)的能量密度从764J/cm增加到1146J/cm时,消融深度从152.7μm增加到489.7μm。相应地,对于以3Hz和0.22ms脉冲宽度运行的钬激光,深度从21μm增加到68μm。我们将此归因于激光能量导致的温度升高。我们通过考虑三种不同的掺铥光纤激光脉冲宽度:0.5ms、0.75ms和1ms,进一步研究了脉冲宽度对消融深度的影响。当脉冲宽度从0.5ms增加到1ms时,消融深度从402.5μm减小到242.6μm。由于较低的水吸收系数,钬激光(70mJ/10Hz)产生的消融深度和温度分布比掺铥光纤激光(70mJ/10Hz)小。文献中的实验结果验证了模拟结果。我们发现,当钬激光设置为0.2J/100Hz、掺铥光纤激光设置为0.4J/50Hz时,钬激光在消融方面表现更好,这是我们在文献中找到的临床激光设置。这表明,除了水对激光的吸收外,激光参数也对温度分布和消融有显著影响。

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