Germán-Díaz Marta, Peña Eva, Núñez-Ramos Raquel, Guijarro María Jesús, Arroba Cristina Marín-Arriscado
Pediatric Gastroenterology, Hepatology and Nutrition Department, Hospital Universitario 12 de Octubre, Madrid, Spain.
Intestinal Rehabilitation Unit, Hospital La Paz, Madrid, Spain.
Nutr Clin Pract. 2025 Apr;40(2):457-464. doi: 10.1002/ncp.11261. Epub 2024 Dec 17.
Both blended tube feed (BTF) and commercial tube feed (CTF) can be administered through a gastrostomy tube (GT). There is very little evidence about using home BTF (HBTF). Nevertheless, families increasingly request this type of nutrition because they attribute some benefits to it. Our objective was to evaluate the efficacy and safety of using HBTF via GT as an alternative to CTF.
Single-center, retrospective, and observational study of patients under 18 years old who underwent GT between 2014 and 2020. We reviewed demographics, anthropometrics, clinical characteristics, and types of diet and gastrointestinal (GI) symptoms over 12 months after the placement of the GT.
Forty patients (40% boys) were included. The median age at GT placement was 15 months (interquartile range 5-57.5). The most common underlying diagnosis was a neurological disorder (45%). In 75% of patients, Nissen fundoplication was performed. At the 12-month follow-up, 18 patients (45%) were receiving 100% HBTF, 14 (35%) were receiving a mixed diet (HBTF + CTF), four (10%) were receiving 100% CTF, and four (10%) were no longer using the GT. Those with a 100% HBTF diet showed a statistically significant higher weight at the 12-month follow-up than those who had received any percentage of CTF. No other statistically significant differences in anthropometric indices or GI symptoms were found between the two groups. Only three cases of mechanical complications were reported.
In our experience, using HBTF via the GT provides an alternative to CTF in pediatric patients who require enteral nutrition.
混合管饲（BTF）和市售管饲（CTF）均可通过胃造口管（GT）给药。关于使用家庭混合管饲（HBTF）的证据非常少。然而，家庭越来越多地要求采用这种营养方式，因为他们认为它有一些益处。我们的目的是评估经GT使用HBTF替代CTF的疗效和安全性。
对2014年至2020年间接受GT置入术的18岁以下患者进行单中心、回顾性观察研究。我们回顾了患者的人口统计学、人体测量学、临床特征以及GT置入后12个月内的饮食类型和胃肠道（GI）症状。
纳入40例患者（40%为男孩）。GT置入时的中位年龄为15个月（四分位间距5 - 57.5）。最常见的潜在诊断是神经疾病（45%）。75%的患者进行了nissen胃底折叠术。在12个月的随访中，18例患者（45%）接受100% HBTF，14例（35%）接受混合饮食（HBTF + CTF），4例（10%）接受100% CTF，4例（10%）不再使用GT。接受100% HBTF饮食的患者在12个月随访时的体重在统计学上显著高于接受任何比例CTF的患者。两组在人体测量指标或GI症状方面未发现其他统计学上的显著差异。仅报告了3例机械并发症。
根据我们的经验，对于需要肠内营养的儿科患者，经GT使用HBTF可作为CTF的一种替代方案。
