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交错练习期间的M1募集对于技能记忆的编码（而非仅仅巩固）很重要。

M1 recruitment during interleaved practice is important for encoding, not just consolidation, of skill memory.

作者信息

Kim Taewon, Kim Hakjoo, Philip Benjamin A, Wright David L

机构信息

Department of Physical Medicine and Rehabilitation, Penn State College of Medicine, Hershey, PA, USA.

Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania, PA, USA.

出版信息

NPJ Sci Learn. 2024 Dec 18;9(1):77. doi: 10.1038/s41539-024-00290-2.

DOI:10.1038/s41539-024-00290-2
PMID:39695110
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11655630/
Abstract

The primary motor cortex (M1) is crucial for motor skill learning. We examined its role in interleaved practice, which enhances retention (vs. repetitive practice) through M1-dependent consolidation. We hypothesized that cathodal transcranial direct current stimulation (ctDCS) to M1 would disrupt retention. We found that ctDCS reduced retention due to weakened encoding during acquisition, not disrupted consolidation. These results highlight M1's broad role in encoding and retention of novel motor skills.

摘要

初级运动皮层（M1）对运动技能学习至关重要。我们研究了它在交错练习中的作用，交错练习通过依赖M1的巩固过程增强记忆保持（与重复练习相比）。我们假设对M1进行阴极经颅直流电刺激（ctDCS）会破坏记忆保持。我们发现，ctDCS由于在习得过程中编码减弱而降低了记忆保持，而非破坏巩固过程。这些结果突出了M1在新运动技能编码和记忆保持中的广泛作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/032f651ffa7c/41539_2024_290_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/b1e0bb9b1df4/41539_2024_290_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/abae18fb96d0/41539_2024_290_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/032f651ffa7c/41539_2024_290_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/b1e0bb9b1df4/41539_2024_290_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/abae18fb96d0/41539_2024_290_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9301/11655630/032f651ffa7c/41539_2024_290_Fig3_HTML.jpg

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