Elliott Helen, Allen A Joy, Forester Nerys D, Graziadio Sara, Jones W S, Lendrem Beverley Clare, Pearce Mark S, Powell Timothy, Scott Jason, Bray Alison
Royal Victoria Infirmary, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK.
Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, UK.
Br J Cancer. 2025 Feb;132(3):276-282. doi: 10.1038/s41416-024-02930-1. Epub 2024 Dec 18.
Mammography has poor sensitivity in dense breast tissue. Retrospective studies suggest that Molecular Breast Imaging (MBI), has superior diagnostic accuracy to mammography in women with very dense breast tissue. Women's perspectives of MBI are unknown, but are crucial to understanding the feasibility of, and routes to, adoption into practice.
Semi-structured interviews with screened and unscreened women explored acceptability of MBI. Data were analysed thematically.
Four themes were generated from nineteen interviews: (1) presumed negative aspects of MBI are acceptable (2) convenience of access, (3) comfort in familiarity and (4) need for shared decisions relating to risk. Presumed negative aspects of MBI, such as radiation dose and forty-minute scan time, were acceptable provided there are benefits. Some participants were concerned about equitable access, such as parking. Participants expressed comfort in existing and familiar screening processes. Participants acknowledged that informing women of their breast density may result in increased anxiety, but it was still felt to be important to ensure women are fully informed of the risks and harms of screening.
Women consider MBI to be an acceptable breast imaging modality. High-quality information enabling informed decision-making is essential.
乳腺钼靶摄影对致密乳腺组织的敏感性较差。回顾性研究表明，分子乳腺成像（MBI）在乳腺组织非常致密的女性中，诊断准确性优于乳腺钼靶摄影。女性对MBI的看法尚不清楚，但对于理解其应用于临床实践的可行性及途径至关重要。
对已接受筛查和未接受筛查的女性进行半结构式访谈，探讨MBI的可接受性。采用主题分析法对数据进行分析。
通过19次访谈得出四个主题：（1）MBI的假定负面因素是可接受的；（2）就诊便利性；（3）熟悉带来的舒适感；（4）需要就风险进行共同决策。只要有好处，MBI的假定负面因素，如辐射剂量和40分钟的扫描时间，都是可以接受的。一些参与者担心能否公平获得服务，如停车问题。参与者对现有的和熟悉的筛查流程表示安心。参与者承认，告知女性其乳腺密度可能会增加焦虑，但仍认为确保女性充分了解筛查的风险和危害很重要。
女性认为MBI是一种可接受的乳腺成像方式。提供高质量信息以实现知情决策至关重要。
