Wilson Charley, Butler Nadia, Quigg Zara, Moore David, Bellis Mark
Liverpool John Moores University, Liverpool, UK.
BMC Med. 2024 Dec 18;22(1):592. doi: 10.1186/s12916-024-03821-1.
Evidence indicates that neurodivergent (ND) populations may be more at risk of experiencing adverse childhood experiences (ACEs), compared to neurotypical (NT) populations. However, this evidence has typically not examined a comprehensive set of ACEs and has only included ND individuals on the basis that they have a diagnosis. Very little research has examined the impacts of ACEs on negative adulthood outcomes for ND populations. The current study aimed to examine the associations between neurodivergence and experiences of ACEs, and the impact of being ND and experiencing ACEs on health, wellbeing, and criminal justice outcomes.
From November 2023 to April 2024, a household survey using representative sampling was undertaken with 5395 residents of an English region aged 18 + years. Neurodivergence status was measured using one self-report item. Nine ACEs were measured using validated self-report items. Outcome measures included: poor general health, low mental wellbeing, ever being arrested, and ever being incarcerated. Multinomial regression models were used to examine relationships between neurodivergence status and ACEs. Binary logistic regression models were used to examine independent relationships between neurodivergence status and ACE count and each outcome measure. Generalised linear models with an estimated marginal means function were used to estimate the increased risk of each outcome for different combinations of neurodivergence and ACE count status (NT less than four ACEs (reference group), NT 4 + ACEs, ND less than four ACEs, ND 4 + ACEs).
A higher proportion of ND individuals experienced each ACE type than NT individuals. While controlling for sociodemographics, ND individuals were more likely to experience a greater number of ACEs than their NT peers. While controlling for sociodemographics, each outcome measure was more likely amongst those who were ND, and each outcome measure except for poor general health was more likely amongst those with higher ACE counts.
The combination of being ND and experiencing ACEs could additively increase risks of experiencing poor wellbeing and criminal justice outcomes by a greater extent than expected. Preventing and responding to ACEs in ND populations should be a priority to reduce risks of poor health, wellbeing, and criminal justice outcomes in this population.
有证据表明,与神经典型(NT)人群相比,神经差异(ND)人群可能更易遭受童年不良经历(ACEs)。然而,这一证据通常未全面考察一系列ACEs,且仅纳入了有诊断结果的ND个体。极少有研究考察ACEs对ND人群成年后负面结果的影响。本研究旨在考察神经差异与ACEs经历之间的关联,以及ND状态和经历ACEs对健康、幸福感和刑事司法结果的影响。
2023年11月至2024年4月,对英国某地区5395名18岁及以上居民进行了一项采用代表性抽样的家庭调查。神经差异状态通过一个自我报告项目进行测量。九个ACEs通过经过验证的自我报告项目进行测量。结果指标包括:总体健康状况差、心理健康水平低、曾被逮捕和曾被监禁。多项回归模型用于考察神经差异状态与ACEs之间的关系。二元逻辑回归模型用于考察神经差异状态与ACE计数以及每个结果指标之间的独立关系。具有估计边际均值函数的广义线性模型用于估计不同神经差异和ACE计数状态组合(NT少于四个ACEs(参照组)、NT 4个及以上ACEs、ND少于四个ACEs、ND 4个及以上ACEs)下每个结果的风险增加情况。
与NT个体相比,更高比例的ND个体经历了每种ACE类型。在控制社会人口统计学因素后,ND个体比其NT同龄人更有可能经历更多的ACEs。在控制社会人口统计学因素后,每个结果指标在ND个体中更有可能出现,除总体健康状况差外,每个结果指标在ACE计数较高的个体中更有可能出现。
ND状态与经历ACEs的结合可能会比预期更大程度地累加增加出现幸福感差和刑事司法结果的风险。预防和应对ND人群中的ACEs应成为降低该人群健康状况差、幸福感差和刑事司法结果风险的优先事项。