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一氧化碳中毒:一例临床病例报告。

Carbon monoxide poisoning: a clinical case report.

作者信息

Baksevice Deimante, Mankute-Use Aida, Bernotaite-Morkune Austeja, Zelbiene Egle

机构信息

Department of Emergency Medicine, Lithuanian University of Health Sciences, A. Mickevičiaus g. 9, Kaunas, LT-44307, Lithuania.

出版信息

Int J Emerg Med. 2024 Dec 18;17(1):186. doi: 10.1186/s12245-024-00777-0.

DOI:10.1186/s12245-024-00777-0
PMID:39695932
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11653981/
Abstract

BACKGROUND

Carbon monoxide (CO) poisoning is a serious yet frequently overlooked condition with diverse and nonspecific clinical presentations. The analysis of Lithuanian statistics reveals fluctuations in patient admissions and consultations through the poisoning center over a four-year period, with notable variations in fatality rates. Despite these trends, CO poisoning remains a significant public health concern due to its potential for severe long-term sequelae or death.

CASE

This case report focuses on two distinct presentations of CO poisoning in a young couple, illustrating the varied manifestations and outcomes of this toxic exposure. The first case describes a 23-year-old male presenting with altered consciousness and neurological symptoms, while the second case involves a 21-year-old pregnant female presenting with cardiovascular symptoms, including Takotsubo cardiomyopathy.

DISCUSSION

Highlights include the challenges in diagnosing CO poisoning; factors influencing the severity and symptoms of CO poisoning; potential complications; and considerations for hyperbaric oxygen therapy (HBO) in severe cases and pregnancy.

CONCLUSION

These cases illustrate the importance of recognizing CO poisoning, advocating for oxygen therapy as the first-line treatment, and calling for further research to improve understanding, treatment, and prevention of this potentially fatal condition.

摘要

背景

一氧化碳(CO)中毒是一种严重但常被忽视的病症,临床表现多样且无特异性。对立陶宛统计数据的分析显示,四年间通过中毒中心收治的患者和会诊情况存在波动,死亡率也有显著差异。尽管有这些趋势,但由于CO中毒可能导致严重的长期后遗症或死亡,它仍是一个重大的公共卫生问题。

病例

本病例报告聚焦于一对年轻夫妇中CO中毒的两种不同表现形式,展示了这种有毒暴露的多种表现和后果。第一个病例描述了一名23岁男性出现意识改变和神经症状,而第二个病例涉及一名21岁孕妇出现心血管症状,包括应激性心肌病。

讨论

重点包括诊断CO中毒的挑战;影响CO中毒严重程度和症状的因素;潜在并发症;以及重症病例和孕期高压氧治疗(HBO)的考量。

结论

这些病例说明了认识CO中毒的重要性,倡导将氧疗作为一线治疗方法,并呼吁开展进一步研究以增进对这种潜在致命病症的理解、治疗和预防。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07af/11653981/d10b7e9241a6/12245_2024_777_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07af/11653981/d10b7e9241a6/12245_2024_777_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/07af/11653981/d10b7e9241a6/12245_2024_777_Fig1_HTML.jpg

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本文引用的文献

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Takotsubo Cardiomyopathy: Current Treatment.应激性心肌病:当前的治疗方法
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Carbon Monoxide Poisoning.一氧化碳中毒。
Crit Care Clin. 2021 Jul;37(3):657-672. doi: 10.1016/j.ccc.2021.03.010.
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The Poisoned Heart: A Case of Takotsubo Cardiomyopathy Induced by Carbon Monoxide Poisoning.《中毒性心脏病:一氧化碳中毒诱发的 Takotsubo 心肌病病例》
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Carbon monoxide poisoning.一氧化碳中毒
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Carbon Monoxide Poisoning.一氧化碳中毒
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