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本文引用的文献

1
Designing and using incentives to support recruitment and retention in clinical trials: a scoping review and a checklist for design.设计和使用激励措施以支持临床试验的招募和保留:范围综述和设计检查表。
Trials. 2019 Nov 9;20(1):624. doi: 10.1186/s13063-019-3710-z.
2
Strategies to improve recruitment to randomised trials.提高随机试验招募率的策略。
Cochrane Database Syst Rev. 2018 Feb 22;2(2):MR000013. doi: 10.1002/14651858.MR000013.pub6.
3
Cost-effectiveness of health research study participant recruitment strategies: a systematic review.健康研究中研究参与者招募策略的成本效益:一项系统评价
Clin Trials. 2014 Oct;11(5):576-83. doi: 10.1177/1740774514540371. Epub 2014 Jun 30.
4
Strategies for increasing recruitment to randomised controlled trials: systematic review.增加随机对照试验招募的策略:系统评价。
PLoS Med. 2010 Nov 9;7(11):e1000368. doi: 10.1371/journal.pmed.1000368.
5
Increasing recruitment to randomised trials: a review of randomised controlled trials.增加随机试验的入组人数:随机对照试验综述
BMC Med Res Methodol. 2006 Jul 19;6:34. doi: 10.1186/1471-2288-6-34.
6
Effects of different monetary incentives on the return rate of a national mail survey of physicians.不同货币激励措施对全国医师邮件调查回复率的影响。
Med Care. 2001 Feb;39(2):197-201. doi: 10.1097/00005650-200102000-00010.

增加经济激励措施可以降低试验招募的成本。

Increasing financial incentives can lower the cost of trial recruitment.

作者信息

Schwartz Alan, Weiner Saul J, Harrod Molly

机构信息

Department of Medical Education, University of Illinois at Chicago, (mc 591) 808 S. Wood St., 986 CME, Chicago, IL, 60612, USA.

VA Center of Innovation for Complex Chronic Healthcare, Jesse Brown VA Medical Center, Chicago, IL, USA.

出版信息

Trials. 2024 Dec 18;25(1):821. doi: 10.1186/s13063-024-08674-w.

DOI:10.1186/s13063-024-08674-w
PMID:39696635
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11653536/
Abstract

Monetary incentives are commonly used to help recruit trial participants. Some studies have found greater recruitment with larger incentives, while others have found smaller incentives more cost-effective in terms of cost per participant. As part of an implementation study, we compared the impact of four approaches to recruitment, three of which involved phone recruitment with varying financial incentives. Adding modest financial incentives reliably increased the recruitment ratio, and greater incentives increased recruitment more than smaller incentives. However, recruiters required less time to obtain agreement to participate when the greater incentive was offered, and these time savings made the greater incentive cost-saving relative to the smaller incentive and cost-effective relative to no incentive. Our results suggest the possibility of a "sweet spot" for financial incentives, and that trial designers should consider pilot-testing incentive levels in the context of their other recruitment costs to determine whether paying participants more may be cost-saving for trial sponsors.

摘要

金钱激励措施通常用于帮助招募试验参与者。一些研究发现,提供更大的激励能招募到更多参与者,而另一些研究则发现,就每位参与者的成本而言,较小的激励措施更具成本效益。作为一项实施研究的一部分,我们比较了四种招募方法的影响,其中三种方法涉及通过电话招募并给予不同的经济激励。增加适度的经济激励确实提高了招募率,而且较大的激励比较小的激励更能增加招募人数。然而,当提供较大激励时,招募人员获得参与同意所需的时间更少,而且这些时间节省使得较大激励相对于较小激励而言节省了成本,相对于不提供激励而言具有成本效益。我们的结果表明存在经济激励的“最佳点”的可能性,并且试验设计者应该在其他招募成本的背景下考虑对激励水平进行预测试,以确定向参与者支付更多报酬是否可能为试验赞助商节省成本。