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在精神科住院环境中,青少年吸食大麻与过去30天内的自杀未遂及自杀意念有关。

Cannabis Vaping Is Associated With Past 30-Day Suicide Attempts and Suicidal Ideation Among Adolescents in a Psychiatric Inpatient Setting.

作者信息

Thomas Sarah A, Thompson Elizabeth C, Maron Micaela M, Meisel Samuel N, Spirito Anthony, Wolff Jennifer C

机构信息

Alpert Medical School of Brown University, Providence, Rhode Island.

Bradley Hasbro Children's Research Center, Providence, Rhode Island.

出版信息

JAACAP Open. 2024 May 10;2(4):263-273. doi: 10.1016/j.jaacop.2024.03.003. eCollection 2024 Dec.

Abstract

OBJECTIVE

Increasing evidence links adolescent cannabis use (CU) to suicidal thoughts and behaviors. CU may be associated with both developing and self-medicating psychiatric symptoms. Although relatively new, cannabis vaping is increasing among adolescents. This chart review investigation evaluated the association between cannabis vaping and suicidal thoughts and behaviors among adolescents experiencing acute psychiatric symptomatology.

METHOD

The sample included 470 adolescents (ages 11-18; 64% biological female) admitted to an inpatient psychiatric hospital between 2021 and 2023. Adolescents completed an assessment battery measuring CU, psychiatric symptoms, and suicidal thoughts and behaviors. Separate regressions tested links between cannabis vaping and 2 outcomes-past 30-day suicide attempt and suicidal ideation (SI)-controlling for age and biological sex.

RESULTS

In this sample, 26.8% reported past 30-day suicide attempts; 44.3% endorsed ever using cannabis, and 31.5% reported past 30-day CU. Of adolescents who ever used cannabis, 30.8% reported their most frequent method was vaping. Vaping as the most frequent cannabis method was associated with past 30-day suicide attempts (adjusted odds ratio = 2.38,  = .002) and greater SI ( = 8.71,  = .020). The association remained significant for suicide attempts, but only marginally significant for SI ( = .087), after controlling for depressive symptoms, impulse control, psychosocial impairment, and past 30-day substance use.

CONCLUSION

Vaping as the most frequent method of CU was significantly associated with suicide attempts and SI. Because data are cross-sectional, causality cannot be inferred. Nonetheless, cannabis vaping is important to assess among adolescents with acute psychiatric concerns because it may place them at higher risk for suicidal thoughts and attempts.

摘要

目的

越来越多的证据表明青少年使用大麻与自杀念头和行为有关。使用大麻可能与精神症状的发展和自我治疗有关。尽管大麻雾化相对较新,但在青少年中的使用正在增加。本图表回顾性调查评估了在有急性精神症状的青少年中,大麻雾化与自杀念头和行为之间的关联。

方法

样本包括2021年至2023年间入住一家住院精神病医院的470名青少年(年龄11 - 18岁;64%为生物学意义上的女性)。青少年完成了一系列评估,测量使用大麻情况、精神症状以及自杀念头和行为。分别进行回归分析,检验大麻雾化与两个结果(过去30天内的自杀未遂和自杀意念)之间的联系,并对年龄和生物学性别进行控制。

结果

在这个样本中,26.8%的人报告过去30天内有自杀未遂;44.3%的人认可曾经使用过大麻,31.5%的人报告过去30天内使用过大麻。在曾经使用过大麻的青少年中,30.8%的人报告他们最常用的方式是雾化。以雾化作为最常用的大麻使用方式与过去30天内的自杀未遂(调整后的优势比 = 2.38,P = .002)和更强的自杀意念(β = 8.71,P = .020)相关。在控制了抑郁症状、冲动控制、社会心理损害和过去30天内的物质使用后,这种关联在自杀未遂方面仍然显著,但在自杀意念方面仅边缘显著(P = .087)。

结论

以雾化作为最常用的使用大麻方式与自杀未遂和自杀意念显著相关。由于数据是横断面的,无法推断因果关系。尽管如此,对于有急性精神问题的青少年,评估大麻雾化情况很重要,因为这可能使他们有更高的自杀念头和自杀未遂风险。

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