Wilson Daisy L, Ahlawat Jyoti, Narayan Mahesh
Department of Chemistry and Biochemistry, the University of Texas at El Paso (UTEP), El Paso, Texas 79968, United States.
Explor Neuroprotective Ther. 2024;4(1):72-81. doi: 10.37349/ent.2024.00071. Epub 2024 Feb 27.
Carbon nanotubes, an emerging class of carbon nanomaterials, possess tremendous potential for application in biotechnology and biomedicine particularly in neurological disorders. Carbon nanotubes owing to their fascinating properties have the potential to revolutionize medicine and technology, particularly in the realm of drug delivery, biosensing, bioimaging, and as therapeutic agents to tackle complex neurological disorders such as Alzheimer's and Parkinson's disease. In this review, a summary of the use of carbon nanotubes for neuropathological outcomes such as alleviating oxidative stress and amyloid formation, which are well-studied molecular outcomes associated with Alzheimer's and Parkinson's disease. In the end, challenges associated with the clinical testing of carbon nanotubes and possible ways to overcome them are highlighted.
碳纳米管是一类新兴的碳纳米材料,在生物技术和生物医学领域,尤其是神经疾病领域具有巨大的应用潜力。碳纳米管因其迷人的特性,有潜力彻底改变医学和技术,特别是在药物递送、生物传感、生物成像领域,以及作为治疗剂来应对诸如阿尔茨海默病和帕金森病等复杂的神经疾病。在这篇综述中,总结了碳纳米管在神经病理学结果方面的应用,比如减轻氧化应激和淀粉样蛋白形成,这些是与阿尔茨海默病和帕金森病相关的经过充分研究的分子结果。最后,强调了与碳纳米管临床试验相关的挑战以及克服这些挑战的可能方法。